VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 11 of 34

COMPLETED Phase 2

Nitrite Supplementation in Long COVID Patients

NCT05618574

COMPLETED NA

Recovery Bridge: Peer Intervention to Bridge Transition Post Discharge

NCT05758376

TERMINATED Phase 2

Leucoselect Phytosome for Neoadjuvant Treatment of Early Stage Lung Cancer

NCT04515004

TERMINATED Phase 1

Alexithymia Intervention for Suicide

NCT05724953

COMPLETED NA

Collaborate2Lose: Involving Support Persons in Weight Management

NCT05448313

COMPLETED NA

Peer-Led Diet and Exercise Intervention

NCT04994938

COMPLETED

The Feasibility of Home-Based Measurement of Circadian Timing for Veterans With TBI and Insomnia

NCT05665764

COMPLETED NA

Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation

NCT05880251

COMPLETED

How do Psychosocial Factors Relate to Completing a Home Exercise Program for Arm and Hand Recovery in Veteran Stroke Survivors?

NCT05616832

COMPLETED NA

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908

COMPLETED NA

Designing a Mobile App to Support Academic Success for Student Veterans

NCT05344092

COMPLETED NA

Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy

NCT05427201

COMPLETED NA

The Relationship Between Irisin and Bone Health in Individuals With Spinal Cord Injury

NCT05319522

TERMINATED NA

Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans

NCT05724498

COMPLETED NA

The DigIT Trial: The Effectiveness and Implementation of a Coached Digital Insomnia Treatment Program in a Regional Healthcare System.

NCT05558475

COMPLETED NA

Pilot of Peers Enhancing Engagement for Pain Services

NCT05681520

COMPLETED NA

Pain and Loneliness

NCT05455476

COMPLETED NA

Neural Underpinnings of Turning

NCT05475236

COMPLETED Phase 4

Diuretics and Volume Overload in Early CKD

NCT05171686

COMPLETED NA

Enhancing Geriatric Pain Care

NCT04560920

COMPLETED NA

Diabetes Disparities: Texting to Extend Treatment (DD-TXT)

NCT04227379

COMPLETED NA

Race-Based Stress Trauma and Empowerment

NCT05422638

COMPLETED NA

Enhancing Skeletal Adaptations to PTH and Exercise

NCT05029128

COMPLETED NA

Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide

NCT04784663

COMPLETED NA

Mindful Hand Hygiene for Healthcare Workers

NCT05261282

COMPLETED NA

Develop and Validation of Measurement-Based Transition Assistance

NCT05384171

COMPLETED NA

Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth

NCT06011759

COMPLETED NA

Health Coaching: A Pilot Trial Among Reintegrating Veterans

NCT05199467

COMPLETED NA

Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression

NCT04002063

COMPLETED NA

Pilot Study of TENS for Ocular Pain

NCT05531643

COMPLETED NA

Developing an Integrative, Recovery-Based, Post-Acute COVID-19 Syndrome (PACS) Psychotherapeutic Intervention

NCT05453201

COMPLETED NA

Substance Use and Loneliness

NCT05338268

COMPLETED NA

Reducing Use of Sleep Medications Assisted by a Digital Insomnia Intervention

NCT05027438

COMPLETED NA

The EMBER Trial for Weight Management Engagement

NCT05424081

COMPLETED NA

Rheumatoid Arthritis Shared Decision Making

NCT05530694

COMPLETED NA

Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions

NCT04922320

COMPLETED NA

BEAST: A Pilot Trial

NCT05416203

COMPLETED NA

Adjunctive Family CBT for Veterans With Anxiety

NCT05340478

COMPLETED NA

Rage Against the Pain to Address Chronic Low Back Pain Among Veterans

NCT05103475

COMPLETED

Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans

NCT05480943

COMPLETED NA

Brasthesis Prosthetic Harness for Women Veterans With Upper Limb Amputations

NCT05179395

COMPLETED NA

Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness

NCT04324944

COMPLETED NA

Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury

NCT04971408

COMPLETED NA

Effects of Neuromodulation and Cognitive Training for Suicide in Veterans (ENACTS)

NCT05231213

COMPLETED Early Phase 1

High Frequency SARS for Neurogenic Bladder and Bowel Emptying

NCT05214378

COMPLETED NA

MEPS-Pain: Personalized Pain Self-management Planning by and for Veterans Pilot Study

NCT04075487

COMPLETED NA

Implementing Group Physical Therapy (PT) for Veterans With Knee Osteoarthritis (Group PT): Function QUERI 2.0

NCT05282927

COMPLETED NA

Feasibility and Acceptability Off The Equus Effect

NCT04159506

COMPLETED

Telehealth Acceptance and Commitment Therapy for Older Veterans Experiencing Pandemic-Related Stress

NCT05433662

TERMINATED Phase 4

CBT-I Augmentation of Medication for Drinking in AUD

NCT04581603

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.