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NCT04446481 · ClinicalTrials.gov registry record · NA

Neurofeedback to Aid Vets' Memory

A NA study of Mild Cognitive Impairment, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
4
Enrollment target
1
Study location

NCT04446481: Completed NA study of Mild Cognitive Impairment, sponsored by VA Office of Research and Development.

NCT04446481 is a NA study of Mild Cognitive Impairment that has completed, run by VA Office of Research and Development. The registered enrollment target is 4 participants, below the 1,271-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04446481, a NA study of Mild Cognitive Impairment, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
4 participants
Enrollment target
1
Study location

Study Summary

Military deployment is associated with increased risk of mild cognitive impairment (MCI). Combat stress related memory deficits has been well documented. Mild cognitive impairment such as memory deficits are the most common and earliest symptoms of Alzheimer's disease and related dementia (ADRD). The complaints about declined memory are common in healthy and cognitively intact civilian older adults, but less understood in aging Veterans. Brain training strategies to enhance cognitive skills and especially memory processes are unmet needs in aging Veterans who are at additional risk for MCI induced by ADRD. Since currently there is no effective drug treatment to stop cognitive decline, non-invasive brain training to boost memory functions in older Veterans is an increasingly attractive option to attenuating decline in memory.

Primary Outcome

alpha power under eyes closed and eyes open are linked to better mental state; likely biomarker for mild cognitive impairment.

Conditions Studied

Interventions

  • DEVICE Neurofeedback

Study Locations (1)

Kentucky

  • Lexington VA Medical Center, Lexington, KY - Lexington

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2022-02-05
Est. Completion 2025-09-30
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT04446481 record still lists

NCT04446481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,271-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which Neurofeedback is the first listed.

NCT04446481 reports a single indexed study location in Kentucky.

Frequently Asked Questions

What is clinical trial NCT04446481 about?

NCT04446481 is a clinical study titled "Neurofeedback to Aid Vets' Memory". Military deployment is associated with increased risk of mild cognitive impairment (MCI). Combat stress related memory deficits has been well documented. Mild cognitive impairment such as memory deficits are the most common and earliest symptoms of Alzheimer's disease and related dementia (ADRD). Th...

What is the current status of trial NCT04446481?

This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2022-02-05. Estimated completion is 2025-09-30.

What conditions does trial NCT04446481 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment.

What interventions are being tested in trial NCT04446481?

The interventions under investigation include: Neurofeedback (DEVICE).

Who is sponsoring clinical trial NCT04446481?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04446481 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Mild Cognitive Impairment

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04446481's enrollment target sits among peer trials

4 204th of 205 higher than 1 of 205 other Mild Cognitive Impairment trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04446481, the US trial registry maintained by the National Library of Medicine. NCT04446481 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.