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NCT05029128 · ClinicalTrials.gov registry record · NA
Enhancing Skeletal Adaptations to PTH and Exercise
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
NCT05029128: Completed NA study, sponsored by VA Office of Research and Development.
NCT05029128 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 18 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05029128, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
Study Summary
Exercise is essential for building and maintaining bone mass and strength, but current exercise recommendations for how to achieve this lack detail on the optimal exercise prescription. Recent studies found that blood calcium level decreases during exercise, and that calcium is mobilized from bone to slow the decline. If this occurs repeatedly during exercise training, it could diminish the potential benefits of exercise to improve bone health. The proposed study will determine whether further research on pre-exercise supplemental calcium to minimize the decline in blood calcium level during exercise is warranted. This research is important for Veterans because they are at increased risk of hip fracture when compared with non-Veterans. Further, because osteoporosis in men is under-recognized and under-treated, providing male (and female) Veterans with more specific exercise and nutrition guidelines has the potential to enhance bone health, reduce fracture risk, and improve quality of life.
Primary Outcome
CTX is a marker of bone resorption. An increase in CTX in response to exercise is evidence of an acute catabolic response of bone.
Interventions
- BEHAVIORAL Endurance exercise intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2025-12-01 |
| Phase | NA |
What the finished NCT05029128 record still lists
NCT05029128 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Endurance exercise intervention is the first listed.
NCT05029128 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05029128 about?
NCT05029128 is a clinical study titled "Enhancing Skeletal Adaptations to PTH and Exercise". Exercise is essential for building and maintaining bone mass and strength, but current exercise recommendations for how to achieve this lack detail on the optimal exercise prescription. Recent studies found that blood calcium level decreases during exercise, and that calcium is mobilized from bone t...
What is the current status of trial NCT05029128?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2023-01-01. Estimated completion is 2025-12-01.
What interventions are being tested in trial NCT05029128?
The interventions under investigation include: Endurance exercise intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT05029128?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05029128's enrollment target sits among peer trials
18 1863rd of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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