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NCT05427201 · ClinicalTrials.gov registry record · NA
Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 31
- Enrollment target
NCT05427201: Completed NA study, sponsored by VA Office of Research and Development.
NCT05427201 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 31 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05427201, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
Study Summary
Veterans with comorbid chronic pain and depression are highly prevalent, have poor functional status and low quality of life, are at increased risk of suicide and lack access to effective treatments. To address this problem, the proposed research will examine the feasibility of a novel approach that integrates repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy with the overall goal of maximizing functional improvement in Veterans with chronic pain and depression. This is an important first-step in preparation for a future randomized efficacy trial. The investigators will also include two cognitive control tasks with concurrent electroencephalography to explore as a potential objective indicator of treatment response. This application addresses a critical need within the Veterans Health Administration and is closely aligned with the focus area of developing suicide prevention treatments that influence participation in life roles.
Primary Outcome
The PROMIS Pain Interference questionnaire consists of 8-items that assess the degree to which pain interferes with various aspects of life, including mobility, social activity, and mood. Items are scored on a 1 ("Not at all") to 5 ("Very much") scale with a range of 8 - 40. These scores are subsequently transcribed to a T-score. PROMIS measures are reported as standardized T-scores with a population mean of 50 and standard deviation of 10. Higher scores indicate greater pain interference. A 10-
Interventions
- BEHAVIORAL Acceptance and Commitment Therapy
- DEVICE Repetitive Transcranial Magnetic Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2023-05-22 |
| Est. Completion | 2025-05-30 |
| Phase | NA |
What the finished NCT05427201 record still lists
NCT05427201 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Acceptance and Commitment Therapy is the first listed.
NCT05427201 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05427201 about?
NCT05427201 is a clinical study titled "Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy". Veterans with comorbid chronic pain and depression are highly prevalent, have poor functional status and low quality of life, are at increased risk of suicide and lack access to effective treatments. To address this problem, the proposed research will examine the feasibility of a novel approach that...
What is the current status of trial NCT05427201?
This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2023-05-22. Estimated completion is 2025-05-30.
What interventions are being tested in trial NCT05427201?
The interventions under investigation include: Acceptance and Commitment Therapy (BEHAVIORAL), Repetitive Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05427201?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05427201's enrollment target sits among peer trials
31 1592nd of 2000 higher than 408 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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