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NCT04971408 · ClinicalTrials.gov registry record · NA
Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury
A NA study of Spinal Cord Injury and Glucose Metabolism, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT04971408: Completed NA study of Spinal Cord Injury and Glucose Metabolism, sponsored by VA Office of Research and Development.
NCT04971408 is a NA study of Spinal Cord Injury and Glucose Metabolism that has completed, run by VA Office of Research and Development. The registered enrollment target is 10 participants, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04971408, a NA study of Spinal Cord Injury and Glucose Metabolism, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
SCI results in higher incidence of heart disease and diabetes and heart disease is the most common cause of death. Chronic inflammation, deleterious changes in vascular structure and impaired glucose metabolism are risk factors that contribute to both heart disease and diabetes. While exercise can help reduce these risk factors, paralysis and impaired accessibility often precludes exercise in persons with SCI. New research in able-bodied persons demonstrates passive heating decreases inflammation and improves vascular function. Similar studies in persons with SCI suggest they may also have the same health benefits however these studies only investigated the impact of short term (one episode) passive heating (as opposed to repeated bouts). Repeated bouts of heat exposure will likely be required to impact chronic inflammation, but this has never been tested in persons with SCI. This study will test the impact of repeated bouts (3x/week) of passive heat stress over a longer term (8 weeks) on inflammation, metabolism and vascular function.
Primary Outcome
Plasma concentration, which was determined using enzyme-linked immunosorbent assays.
Conditions Studied
Interventions
- OTHER Control
- OTHER passive heat stress
Study Locations (1)
Texas
- South Texas Health Care System, San Antonio, TX - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2022-07-01 |
| Est. Completion | 2024-06-30 |
| Phase | NA |
What the finished NCT04971408 record still lists
NCT04971408 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (88% lower).
The record links to 4 conditions, with Spinal Cord Injury appearing as the primary indexed condition, and to 2 interventions - of which Control is the first listed.
NCT04971408 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04971408 about?
NCT04971408 is a clinical study titled "Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury". SCI results in higher incidence of heart disease and diabetes and heart disease is the most common cause of death. Chronic inflammation, deleterious changes in vascular structure and impaired glucose metabolism are risk factors that contribute to both heart disease and diabetes. While exercise can h...
What is the current status of trial NCT04971408?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2022-07-01. Estimated completion is 2024-06-30.
What conditions does trial NCT04971408 study?
This clinical trial studies the following conditions: Spinal Cord Injury, Glucose Metabolism, Chronic Inflammation, Endothelial Function.
What interventions are being tested in trial NCT04971408?
The interventions under investigation include: Control (OTHER), passive heat stress (OTHER).
Who is sponsoring clinical trial NCT04971408?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04971408 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04971408's enrollment target sits among peer trials
10 82nd of 99 higher than 8 of 99 other Spinal Cord Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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