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NCT06758414 · ClinicalTrials.gov registry record · NA
CBT-CP for Veterans With SMI
A NA study of Schizophrenia and Chronic Pain, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 190
- Enrollment target
- 1
- Study location
NCT06758414: Recruiting NA study of Schizophrenia and Chronic Pain, sponsored by VA Office of Research and Development.
NCT06758414 is a NA study of Schizophrenia and Chronic Pain that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 190 participants, below the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (13% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06758414, a NA study of Schizophrenia and Chronic Pain, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 190 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic musculoskeletal pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic musculoskeletal pain leads to poorer mental and physical health-related functioning, representing a critical obstacle to rehabilitation and recovery for SMI Veterans. Despite known high prevalence rates of chronic pain in SMI populations, there is little research to evaluate nonpharmacological pain management strategies in this population. This study aims to address this research and clinical gap by testing the efficacy of Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) - a VA evidence-based psychotherapy for chronic pain - in Veterans with SMI and chronic low back pain. The study will primarily evaluate the impact of CBT-CP on pain-related functioning, quality of life, and pain severity. This study will also examine relationships between pain and mental health symptoms, and how these relationships may change with CBT-CP completion.
Primary Outcome
The Brief pain Inventory - Interference subscale (BPI-INT) is a 9-item questionnaire measuring pain-relate interference. Respondents answer the degree to which pain interferes with mood/affect and physical activity on a scale from 0 (not at all) to 10 (all the time/completely). An average score is calculated, with a score of \>= 4 indicating moderate to severe pain interference. The instrument has excellent psychometric properties and is regularly used in pain research and clinical practice.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy for Chronic Pain (CBT-CP)
- BEHAVIORAL Health & Wellness (H&W)
Study Locations (1)
Maryland
- Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2026-02-01 |
| Est. Completion | 2029-09-30 |
| Phase | NA |
What NCT06758414 shows while recruiting
NCT06758414 is an interventional study that assigns participants to a tested intervention. The registered 190 participants enrollment target is mid-sized for trials with a published cap, below the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (13% lower).
The record links to 5 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) is the first listed.
NCT06758414 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06758414 about?
NCT06758414 is a clinical study titled "CBT-CP for Veterans With SMI". Chronic musculoskeletal pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic musculoskeletal pain leads to poorer mental and physical health-related functioning, representing a critical obstacle to rehabilitation and recovery for SMI Veterans. De...
What is the current status of trial NCT06758414?
This trial is currently recruiting. It is a NA study. The enrollment target is 190 participants. The study started on 2026-02-01. Estimated completion is 2029-09-30.
What conditions does trial NCT06758414 study?
This clinical trial studies the following conditions: Schizophrenia, Chronic Pain, Bipolar Disorder, Psychotic Disorders, Affective Disorders, Psychotic.
What interventions are being tested in trial NCT06758414?
The interventions under investigation include: Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) (BEHAVIORAL), Health & Wellness (H&W) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06758414?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06758414 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06758414's enrollment target sits among peer trials
190 91st of 315 higher than 225 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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