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NCT06419439 · ClinicalTrials.gov registry record · Phase 2

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

A Phase 2 study of Depression and Chronic Low Back Pain, sponsored by VA Office of Research and Development.

Recruiting
Registry status
Phase 2
Development phase
44
Enrollment target
1
Study location

NCT06419439 is a Phase 2 study of Depression and Chronic Low Back Pain that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 44 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06419439, a Phase 2 study of Depression and Chronic Low Back Pain, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
Phase 2
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.

Conditions Studied

Depression Chronic Low Back Pain

Interventions

  • DRUG Ketamine hydrochloride
  • BEHAVIORAL Minimally Enhanced Usual Care
  • BEHAVIORAL Brief narrative intervention

Study Locations (1)

Michigan

  • VA Ann Arbor Healthcare System, Ann Arbor, MI - Ann Arbor

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2025-12-03
Est. Completion 2029-06-30
Phase Phase 2

Sponsor

VA Office of Research and Development

1,668 total trials

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What the Registry Record Tells You About NCT06419439

The ClinicalTrials.gov registry entry for NCT06419439 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 3 interventions - of which Ketamine hydrochloride is the first listed.

NCT06419439 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT06419439 about?

NCT06419439 is a clinical study titled "Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression". This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.

What is the current status of trial NCT06419439?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2025-12-03. Estimated completion is 2029-06-30.

What conditions does trial NCT06419439 study?

This clinical trial studies the following conditions: Depression, Chronic Low Back Pain.

What interventions are being tested in trial NCT06419439?

The interventions under investigation include: Ketamine hydrochloride (DRUG), Minimally Enhanced Usual Care (BEHAVIORAL), Brief narrative intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT06419439?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06419439 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.