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NCT06574009 · ClinicalTrials.gov registry record · Phase 4

Better Options for Chronic Cancer Pain

A Phase 4 study of Chronic Pain and Opioid Dependence, sponsored by VA Office of Research and Development.

Recruiting
Registry status
Phase 4
Development phase
294
Enrollment target
2
Study locations

NCT06574009 is a Phase 4 study of Chronic Pain and Opioid Dependence that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 294 participants, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06574009, a Phase 4 study of Chronic Pain and Opioid Dependence, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
Phase 4
Development phase
294 participants
Enrollment target
2
Study locations

Study Summary

This proposal is relevant to the 240,000 cancer survivors who continue to use opioids long after they have successfully completed treatment for cancer at the VHA, placing them at risk of opioid addiction and overdose, and other opioid-related problems. Yet, there are no programs at the VHA to help them find alternatives to opioids, nor evidence to inform the choice of interventions. This study will meet these needs by examining four interventions that are effective at reducing opioid use in patients with chronic musculoskeletal pain but have yet to be tested in cancer survivors on long term opioid therapy. The proposed work is relevant to the VHA Pain Office's mission to provide Veterans better pain management while limiting the risks of long-term opioid therapy and it aligns with VHA Research and Development's priority to examine clinical interventions for tapering opioids. Successful completion this project will keep VHA at the forefront of the battle against the opioid epidemic with a strategy that may be adapted to address the same needs in non-Veterans.

Interventions

  • BEHAVIORAL Multimodal pain care
  • DRUG Medication optimization
  • DEVICE Buprenorphine rotation
  • OTHER Opioid tapering

Study Locations (2)

Indiana

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN - Indianapolis

Michigan

  • VA Ann Arbor Healthcare System, Ann Arbor, MI - Ann Arbor

Trial Details

FieldValue
Enrollment Target 294 participants
Start Date 2025-10-07
Est. Completion 2029-12-31
Phase Phase 4

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT06574009

The ClinicalTrials.gov registry entry for NCT06574009 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 294 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 771-participant average among 301 other Chronic Pain trials with a reported enrollment target (62% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 4 interventions - of which Multimodal pain care is the first listed.

NCT06574009 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Indiana, Michigan.

Frequently Asked Questions

What is clinical trial NCT06574009 about?

NCT06574009 is a clinical study titled "Better Options for Chronic Cancer Pain". This proposal is relevant to the 240,000 cancer survivors who continue to use opioids long after they have successfully completed treatment for cancer at the VHA, placing them at risk of opioid addiction and overdose, and other opioid-related problems. Yet, there are no programs at the VHA to help t...

What is the current status of trial NCT06574009?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 294 participants. The study started on 2025-10-07. Estimated completion is 2029-12-31.

What conditions does trial NCT06574009 study?

This clinical trial studies the following conditions: Chronic Pain, Opioid Dependence, Cancer Survivor.

What interventions are being tested in trial NCT06574009?

The interventions under investigation include: Multimodal pain care (BEHAVIORAL), Medication optimization (DRUG), Buprenorphine rotation (DEVICE), Opioid tapering (OTHER).

Who is sponsoring clinical trial NCT06574009?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06574009 being conducted?

This trial has 2 study locations across Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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