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NCT06580457 · ClinicalTrials.gov registry record · NA
Personalized Approach to Healthy Use and Recovery (PATH) Trial
A NA study of Substance Use Disorder, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT06580457: Recruiting NA study of Substance Use Disorder, sponsored by VA Office of Research and Development.
NCT06580457 is a NA study of Substance Use Disorder that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 74 participants, below the 818-participant average among 18 other Substance Use Disorder trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06580457, a NA study of Substance Use Disorder, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
An important part of substance use treatment for many people is learning what triggers their substance use and urges, and how they can better manage those triggers. In this study, the investigators will generate a model for each individual that shows likely causal links between their substance use, urges, and comorbid symptoms (e.g., anxiety, depression, and PTSD), and the investigators will examine these models as a group to draw conclusions about common causes for substance use (and recovery) among Veterans with substance use disorders. The investigators will also test whether receiving a personal model and clinical feedback improves substance use disorder and comorbid symptom outcomes. Results will include both patient-reported and statistically-determined causes of substance use for individuals and groups, clinical impact of a personalized model and feedback session, and participant feedback about the relevance of this study and intervention.
Primary Outcome
Substance use will be measured as number of days each substance was used in the past 30 days using National Survey on Drug Use and Health questions. Substances measured are nicotine, alcohol, cannabis, cocaine/crack, heroin, hallucinogens, inhalants, methamphetamine, pain relievers, tranquilizers, sedatives, and prescription stimulants. For alcohol, we will also obtain number of drinks consumed on each day, and will analyze whether average number of drinks per drinking day has changed during eac
Conditions Studied
Interventions
- BEHAVIORAL Personal Causal Model + Personalized Feedback
Study Locations (1)
Minnesota
- Minneapolis VA Health Care System, Minneapolis, MN - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2030-03-29 |
| Phase | NA |
What NCT06580457 shows while recruiting
NCT06580457 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 818-participant average among 18 other Substance Use Disorder trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Substance Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Personal Causal Model + Personalized Feedback is the first listed.
NCT06580457 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06580457 about?
NCT06580457 is a clinical study titled "Personalized Approach to Healthy Use and Recovery (PATH) Trial". An important part of substance use treatment for many people is learning what triggers their substance use and urges, and how they can better manage those triggers. In this study, the investigators will generate a model for each individual that shows likely causal links between their substance use, ...
What is the current status of trial NCT06580457?
This trial is currently recruiting. It is a NA study. The enrollment target is 74 participants. The study started on 2025-10-01. Estimated completion is 2030-03-29.
What conditions does trial NCT06580457 study?
This clinical trial studies the following conditions: Substance Use Disorder.
What interventions are being tested in trial NCT06580457?
The interventions under investigation include: Personal Causal Model + Personalized Feedback (BEHAVIORAL).
Who is sponsoring clinical trial NCT06580457?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06580457 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06580457's enrollment target sits among peer trials
74 13th of 18 higher than 6 of 18 other Substance Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Substance Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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