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NCT04829110 · ClinicalTrials.gov registry record · NA
Alcohol Induced de Novo Lipogenesis in Women
A NA study of Liver Metabolism, sponsored by University of Texas Southwestern Medical Center.
- Active
- Registry status
- NA
- Development phase
- 27
- Enrollment target
- 1
- Study location
NCT04829110 is a NA study of Liver Metabolism that is active but no longer recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 27 participants. The trial reports 1 study location across 1 state.
The verdict
NCT04829110, a NA study of Liver Metabolism, is active but no longer recruiting, sponsored by University of Texas Southwestern Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is cross-sectional is design. In the first Aim of this study, 5 women and 5 men will be asked to consume 2g/kg of \[2H\]water (a.k.a. deuterium oxide or heavy water) which incorporates 2H tracers into newly synthesized fatty acids and triglycerides. Deuterated water is not radioactive and has a long history of application in human studies. Researchers will collect blood samples 2 hours before and 5 hours after the participants consume 20 grams of alcohol as vodka to measure alcohol induced hepatic de novo lipogenesis (DNL) in both men in women. In addition, for Aim 2 researchers will recruit an additional 10 women who will be randomized into one of two groups who will consume a beverage containing vodka and sucrose, or sucrose alone. Aim 2 will be identical to the experimental scheme in Aim 2 in order to determine if sucrose enhances the effects of vodka on hepatic DNL.
Conditions Studied
Interventions
- OTHER ETOH
- OTHER Sucrose
Study Locations (1)
Texas
- School of Health Professions at UTSW - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2021-11-11 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04829110
The ClinicalTrials.gov registry entry for NCT04829110 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Liver Metabolism appearing as the primary indexed condition, and to 2 interventions - of which ETOH is the first listed.
NCT04829110 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT04829110 about?
NCT04829110 is a clinical study titled "Alcohol Induced de Novo Lipogenesis in Women". The study is cross-sectional is design. In the first Aim of this study, 5 women and 5 men will be asked to consume 2g/kg of \[2H\]water (a.k.a. deuterium oxide or heavy water) which incorporates 2H tracers into newly synthesized fatty acids and triglycerides. Deuterated water is not radioactive and ...
What is the current status of trial NCT04829110?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 27 participants. The study started on 2021-11-11. Estimated completion is 2026-03-31.
What conditions does trial NCT04829110 study?
This clinical trial studies the following conditions: Liver Metabolism.
What interventions are being tested in trial NCT04829110?
The interventions under investigation include: ETOH (OTHER), Sucrose (OTHER).
Who is sponsoring clinical trial NCT04829110?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04829110 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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