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NCT04178005 · ClinicalTrials.gov registry record · Phase 4

Cladribine Tablets After Treatment With Natalizumab (CLADRINA)

A Phase 4 study of Multiple Sclerosis, sponsored by University of Texas Southwestern Medical Center.

Active
Registry status
Phase 4
Development phase
40
Enrollment target
2
Study locations

NCT04178005 is a Phase 4 study of Multiple Sclerosis that is active but no longer recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 40 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT04178005, a Phase 4 study of Multiple Sclerosis, is active but no longer recruiting, sponsored by University of Texas Southwestern Medical Center.

ACTIVE NOT RECRUITING
Registry status
Phase 4
Development phase
40 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to generate hypotheses regarding the safety, efficacy, and immunological impact of cladribine tablets after treatment with natalizumab in patients with relapsing-remitting multiple sclerosis (RRMS) and active secondary progressive multiple sclerosis (active SPMS).

Conditions Studied

Multiple Sclerosis

Interventions

  • DRUG Cladribine

Study Locations (2)

Kansas

  • College Park Family Care Center Physicians Group - Overland Park

Texas

  • UT Southwestern Medical center - Dallas

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-02-19
Est. Completion 2026-12
Phase Phase 4

Sponsor

University of Texas Southwestern Medical Center

837 total trials

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What the Registry Record Tells You About NCT04178005

The ClinicalTrials.gov registry entry for NCT04178005 describes a study currently listed as active not recruiting, categorized as Phase 4. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (93% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Cladribine is the first listed.

NCT04178005 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Kansas, Texas.

Frequently Asked Questions

What is clinical trial NCT04178005 about?

NCT04178005 is a clinical study titled "Cladribine Tablets After Treatment With Natalizumab (CLADRINA)". The purpose of this study is to generate hypotheses regarding the safety, efficacy, and immunological impact of cladribine tablets after treatment with natalizumab in patients with relapsing-remitting multiple sclerosis (RRMS) and active secondary progressive multiple sclerosis (active SPMS).

What is the current status of trial NCT04178005?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2020-02-19. Estimated completion is 2026-12.

What conditions does trial NCT04178005 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT04178005?

The interventions under investigation include: Cladribine (DRUG).

Who is sponsoring clinical trial NCT04178005?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04178005 being conducted?

This trial has 2 study locations across Kansas, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.