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NCT02791880 · ClinicalTrials.gov registry record

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

A clinical trial of Stroke and Heart Failure, sponsored by University of Texas Southwestern Medical Center.

Active
Registry status
62
Enrollment target
3
Study locations

NCT02791880: Active study of Stroke and Heart Failure, sponsored by University of Texas Southwestern Medical Center.

NCT02791880 is a study of Stroke and Heart Failure that is active but no longer recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 62 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02791880, a study of Stroke and Heart Failure, is active but no longer recruiting, sponsored by University of Texas Southwestern Medical Center.

ACTIVE NOT RECRUITING
Registry status
62 participants
Enrollment target
3
Study locations

Study Summary

In the last decade, transcatheter aortic valve replacement (TAVR) has become an increasingly utilized alternative procedure for replacing a stenotic aortic valve. This study collects clinical information, DNA, blood and urine samples (throughout procedural hospitalization) in order to investigate the incidence of acute kidney injury (AKI) in patients undergoing TAVR and to identify key clinical and procedural predictors of AKI. This study seeks to identify blood and urine biomarkers that can be used for early detection of AKI around the time of the procedure. The study seeks to assess for novel genetic variants associated with development of AKI after TAVR. Finally the study seeks to assess for novel genetic variants and biomarkers that are associated with adverse cardiovascular events after TAVR and to further explore how these events may inter-relate with acute kidney injury.

Primary Outcome

Data will be collected from electronic medical records; data points to be collected for this measurement include serum creatinine

Conditions Studied

Stroke Heart Failure Acute Kidney Injury Myocardial Infarction Arrhythmias, Cardiac Renal Insufficiency, Chronic

Interventions

  • PROCEDURE Transcatheter Aortic Valve Replacement

Study Locations (3)

Texas

  • Parkland Health & Hospital Systems - Dallas
  • University of Texas Southwestern Medical Center - Dallas
  • William J. Clements University Hospital - Dallas

Trial Details

FieldValue
Enrollment Target 62 participants
Start Date 2016-10-25
Est. Completion 2031-03-31
University of Texas Southwestern Medical Center

837 total trials

What the registry record for NCT02791880 still lists

NCT02791880 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).

The record links to 6 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Transcatheter Aortic Valve Replacement is the first listed.

NCT02791880 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT02791880 about?

NCT02791880 is a clinical study titled "Acute Kidney Injury Genomics and Biomarkers in TAVR Study". In the last decade, transcatheter aortic valve replacement (TAVR) has become an increasingly utilized alternative procedure for replacing a stenotic aortic valve. This study collects clinical information, DNA, blood and urine samples (throughout procedural hospitalization) in order to investigate th...

What is the current status of trial NCT02791880?

This trial is currently active not recruiting. The enrollment target is 62 participants. The study started on 2016-10-25. Estimated completion is 2031-03-31.

What conditions does trial NCT02791880 study?

This clinical trial studies the following conditions: Stroke, Heart Failure, Acute Kidney Injury, Myocardial Infarction, Arrhythmias, Cardiac.

What interventions are being tested in trial NCT02791880?

The interventions under investigation include: Transcatheter Aortic Valve Replacement (PROCEDURE).

Who is sponsoring clinical trial NCT02791880?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02791880 being conducted?

This trial has 3 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02791880's enrollment target sits among peer trials

62 204th of 454 higher than 250 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02791880, the US trial registry maintained by the National Library of Medicine. NCT02791880 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.