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NCT06002204 · ClinicalTrials.gov registry record
Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
A clinical trial of Depression and Bipolar Disorder, sponsored by University of Texas Southwestern Medical Center.
- Active
- Registry status
- 6,000
- Enrollment target
- 1
- Study location
NCT06002204: Active study of Depression and Bipolar Disorder, sponsored by University of Texas Southwestern Medical Center.
NCT06002204 is a study of Depression and Bipolar Disorder that is active but no longer recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 6,000 participants, above the 777-participant average among 679 other Depression trials with a reported enrollment target (672% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06002204, a study of Depression and Bipolar Disorder, is active but no longer recruiting, sponsored by University of Texas Southwestern Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 6,000 participants
- Enrollment target
- 1
- Study location
Study Summary
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to antidepressant treatment response (remission, recurrence, relapse and individual outcomes in depressive disorders) and resilience. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participant specific parameters - socio-demographic (age, sex, gender, race, ethnicity, economic); life habits (physical activity, substance use); clinical (medical history, anxious depression, early life trauma), biological (biomarkers in blood, saliva, urine, stool), behavioral (cognitive, emotional), neurophysiological (EEG), and neuroimaging (magnetic resonance imaging; MRI) with the goal of developing the most robust predictive models of depression treatment response and of outcomes.
Primary Outcome
Longitudinal changes in depression severity measured by Patient Health Questionnaire (PHQ-9) for non-psychotic depressive disorders.
Conditions Studied
Interventions
- OTHER Observational Study
Study Locations (1)
Texas
- UT Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6,000 participants |
| Start Date | 2024-03-01 |
| Est. Completion | 2035-02 |
What the registry record for NCT06002204 still lists
NCT06002204 is an observational study that tracks outcomes without assigning an intervention. Its 6,000 participants enrollment target places it among the larger protocols in the corpus, above the 777-participant average among 679 other Depression trials with a reported enrollment target (672% higher).
The record links to 6 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Observational Study is the first listed.
NCT06002204 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06002204 about?
NCT06002204 is a clinical study titled "Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression". SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to antidepressant treatment respons...
What is the current status of trial NCT06002204?
This trial is currently active not recruiting. The enrollment target is 6,000 participants. The study started on 2024-03-01. Estimated completion is 2035-02.
What conditions does trial NCT06002204 study?
This clinical trial studies the following conditions: Depression, Bipolar Disorder, Treatment-Resistant Depression, Mood Disorders, Mental Disorders.
What interventions are being tested in trial NCT06002204?
The interventions under investigation include: Observational Study (OTHER).
Who is sponsoring clinical trial NCT06002204?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06002204 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06002204's enrollment target sits among peer trials
6,000 12th of 679 higher than 668 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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