University of Texas Southwestern Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Texas Southwestern Medical Center sits in the top decile of US sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count).

837 total trials 162 currently recruiting 503 completed early-phase tilt top decile by trial count

University of Texas Southwestern Medical Center: 837 sponsored US clinical trials, 162 recruiting.

University of Texas Southwestern Medical Center sponsors 837 registered US clinical trials on ClinicalTrials.gov, 162 of them currently recruiting, and 503 completed. 126 of these trials are in Phase 3-4 (later-stage) and 228 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 9 trials.

Top-decile sponsor footprint

University of Texas Southwestern Medical Center ranks in the top decile of sponsors by registered trial count (#39 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 46/100

503 of 608 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (82.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

837 total, page 16 of 17

COMPLETED NA

Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression

NCT00703209

COMPLETED NA

The Efficacy of Hand Narrow-Band Ultraviolet B (NBUVB) Versus Excilite Treatment in Vitiligo After Minigrafting on the Dorsal Hands

NCT00622180

COMPLETED Phase 3

Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes

NCT00591006

COMPLETED Phase 3

Pilot Trial of Deferasirox in the Treatment of Porphyria Cutanea Tarda

NCT00599326

COMPLETED

Neurophysiological Studies in Schizophrenia and Psychiatric Disorders

NCT01384604

COMPLETED NA

Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops

NCT00610480

COMPLETED Phase 4

Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia

NCT00690235

TERMINATED Phase 4

Sodium Restriction in the Management of Cirrhotic Ascites

NCT00548366

COMPLETED NA

Effect of Dietary Macronutrient Composition

NCT01371396

COMPLETED

Role of Pancreatic Triglyceride Content in Beta-cell Function

NCT00602953

COMPLETED

Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort

NCT00344903

COMPLETED

Stress, Hypothalamic-pituitary-adrenal (HPA) Dysfunction, and Relapse in Alcoholism

NCT00744588

COMPLETED

Non-Interventional F-Two Isoprostane Trial (NIFTI)

NCT00505908

TERMINATED NA

The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation

NCT00680290

COMPLETED Phase 2

Erlotinib and SBRT in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT00547105

TERMINATED Phase 3

Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon

NCT00642694

COMPLETED Phase 1

Oral Misoprostol for Labor Augmentation: A Pilot Study

NCT00906126

COMPLETED

Impulsivity, Neural Deficits and Cocaine Addiction

NCT00744601

COMPLETED Phase 4

Quetiapine for Bipolar Disorder and Alcohol Dependence

NCT00457197

COMPLETED

Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty

NCT00744796

COMPLETED Phase 3

Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica

NCT01391858

COMPLETED Phase 4

Acetaminophen (Tylenol) for Mood and Memory Changes Associated With Corticosteroid Therapy

NCT00377364

COMPLETED NA

A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence

NCT00377299

TERMINATED NA

Duration of The Honeymoon Phase of Type 1 Diabetes: A Comparison of Insulins Detemir, Glargine and NPH

NCT00564018

COMPLETED Phase 1

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

NCT00547339

TERMINATED Phase 1

Pharmacokinetics of Low Dose Ketamine Infusion

NCT00618397

COMPLETED Phase 2

Safety and Efficacy of Cellcept and Avonex as Combination Treatment in Multiple Sclerosis

NCT00324506

COMPLETED NA

Novel Therapies for Metabolic Complications of Lipodystrophies

NCT00457938

COMPLETED Phase 2

RFT-5-dgA in Patients With Metastatic Melanoma

NCT00314093

COMPLETED Phase 2

Trial of Leptin Replacement Therapy in Patients With Lipodystrophy

NCT00896298

COMPLETED Phase 2

Cholic Acid for Hepatic Steatosis in Lipodystrophy

NCT00457639

TERMINATED Phase 2

Pharmacokinetic Response to BPI in Burns

NCT00462904

COMPLETED Phase 4

Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes

NCT00280774

COMPLETED

Clinical Outcomes After AcrySof® ReStor IOL Surgery in Faculty Practice at UTSW Medical Center at Dallas: A Retrospective Review

NCT00344578

COMPLETED Phase 4

Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency

NCT00280293

COMPLETED Phase 2

Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma

NCT00295503

COMPLETED NA

Effects of Systane Versus Saline in Maintaining Tear Film Stability at Determined Time Points

NCT00345241

TERMINATED

A Prospective Clinical Research Project Evaluating The Effects of Soft Contact Lenses on Higher Order Visual Aberrations

NCT00344864

COMPLETED Phase 4

An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence

NCT00223210

TERMINATED Phase 4

Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes

NCT00283309

COMPLETED Phase 4

Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression

NCT00608543

COMPLETED

Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence

NCT00300235

COMPLETED NA

Laparoscopic Simulator Training and Its Impact on Surgical Education

NCT00555243

COMPLETED NA

Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial

NCT00745849

COMPLETED Phase 4

Naltrexone for Bipolar Disorder and Alcohol Dependence

NCT00223275

COMPLETED

Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses

NCT00345085

COMPLETED NA

Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both

NCT00461968

COMPLETED NA

Assessment of Cognitive Functioning Before and After Treatment With Duloxetine

NCT00933439

COMPLETED Phase 4

Levetiracetam for Neuroprotection Against Corticosteroid-induced Hippocampal Dysfunction: A Proof of Concept Study

NCT00223223

COMPLETED Phase 4

Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride

NCT00424762

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Phase Distribution

PhaseTrial count
Phase 1 106
Phase 2 122
Phase 3 28
Phase 4 98

What is open in the University of Texas Southwestern Medical Center pipeline

162 recruiting of 837 indexed (19% open); 503 completed (60%).

Phase mix: 126 late (III/IV) vs 228 early (I/II) (early-phase heavy).

Top condition: Hypertension (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Texas Southwestern Medical Center: open-pipeline peers nationwide

Peers matched on 837 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of Texas Southwestern Medical CenterUniversity of UtahUniversity of ChicagoIndiana UniversityDana-Farber Cancer InstituteCalifornia Polytechnic State University-San Luis ObispoPhoenix Children's HospitalAnn & Robert H Lurie Children's Hospital of ChicagoVanderbilt University Medical Center
University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Texas Southwestern Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 837 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this University of Texas Southwestern Medical Center page

837 registered trials is a research-attention snapshot, not an endorsement of University of Texas Southwestern Medical Center or any single study.

  • 162 of University of Texas Southwestern Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition University of Texas Southwestern Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of Texas Southwestern Medical Center pipeline card: 837 registered trials from official public datasets.Report a data error.