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NCT00377364 · ClinicalTrials.gov registry record · Phase 4
Acetaminophen (Tylenol) for Mood and Memory Changes Associated With Corticosteroid Therapy
A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
NCT00377364 is a Phase 4 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 30 participants.
The verdict
NCT00377364, a Phase 4 study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
Study Summary
Studies in humans and animals support that stress and/or elevations in corticosteroids lead to changes in hippocampal structure and functioning. This is important as patients with major depression frequently have elevated cortisol, and millions of patients receive prescription corticosteroids (e.g. prednisone). Both depression and corticosteroid therapy are associated with memory impairment and hippocampal atrophy. Our research uses corticosteroid-treated patients to explore interventions that might protect the brain from the effects of stress or corticosteroids. We propose to give 30 corticosteroid-treated asthma patients acetaminophen or placebo. Between group differences in mood, memory and other neurocognitive measures will serve as outcome measures.
Interventions
- DRUG Drug: Acetaminophen, Drug: Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2006-11 |
| Est. Completion | 2008-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00377364
The ClinicalTrials.gov registry entry for NCT00377364 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Drug: Acetaminophen, Drug: Placebo is the first listed.
NCT00377364 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00377364 about?
NCT00377364 is a clinical study titled "Acetaminophen (Tylenol) for Mood and Memory Changes Associated With Corticosteroid Therapy". Studies in humans and animals support that stress and/or elevations in corticosteroids lead to changes in hippocampal structure and functioning. This is important as patients with major depression frequently have elevated cortisol, and millions of patients receive prescription corticosteroids (e.g. ...
What is the current status of trial NCT00377364?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2006-11. Estimated completion is 2008-10.
What interventions are being tested in trial NCT00377364?
The interventions under investigation include: Drug: Acetaminophen, Drug: Placebo (DRUG).
Who is sponsoring clinical trial NCT00377364?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
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