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NCT00280774 · ClinicalTrials.gov registry record · Phase 4
Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes
A Phase 4 study of Physiological Effects of Drugs, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT00280774 is a Phase 4 study of Physiological Effects of Drugs that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 20 participants, below the 367-participant average among 6 other Physiological Effects of Drugs trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00280774, a Phase 4 study of Physiological Effects of Drugs, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to determine if patients on corticosteroids who are given memantine will show improvement in memory compared to those receiving placebo (an inactive substance). This research also seeks to determine if such patients, when given memantine, will experience improvement in manic/hypomanic symptoms (feelings of agitation, overexcitement, or hyperactivity) and/or depressive symptoms. Subjects will be randomized to a crossover trial of memantine and placebo for 8 weeks, followed by a 4 week washout and then 8 more weeks of the study medication. Memantine and placebo will start at 5 mg/day for one week, increased to 5 mg twice a day in the second week. During the third week patients will take 10 mg in the morning and 5 mg in the evening. At weeks 4-8, patients will take 10 mg twice a day. One 8 week course of study medication will be memantine and the other 8 week course of study medication will be placebo, both assigned in a random fashion.
Conditions Studied
Interventions
- DRUG Memantine
Study Locations (1)
Texas
- Parkland Health and Hospital System (Asthma, Allergy, & Arthritis Clinics) - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2006-03 |
| Est. Completion | 2007-02 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00280774
The ClinicalTrials.gov registry entry for NCT00280774 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 367-participant average among 6 other Physiological Effects of Drugs trials with a reported enrollment target (95% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Physiological Effects of Drugs appearing as the primary indexed condition, and to 1 intervention - of which Memantine is the first listed.
NCT00280774 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT00280774 about?
NCT00280774 is a clinical study titled "Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes". The purpose of this research is to determine if patients on corticosteroids who are given memantine will show improvement in memory compared to those receiving placebo (an inactive substance). This research also seeks to determine if such patients, when given memantine, will experience improvement i...
What is the current status of trial NCT00280774?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2006-03. Estimated completion is 2007-02.
What conditions does trial NCT00280774 study?
This clinical trial studies the following conditions: Physiological Effects of Drugs.
What interventions are being tested in trial NCT00280774?
The interventions under investigation include: Memantine (DRUG).
Who is sponsoring clinical trial NCT00280774?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00280774 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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