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NCT00610480 · ClinicalTrials.gov registry record · NA
Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops
A NA study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT00610480: Completed NA study, sponsored by University of Texas Southwestern Medical Center.
NCT00610480 is a NA study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00610480, a NA study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
The goal of this research is to evaluate and compare the effectiveness of Systane® versus Optive™ on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the possible application for this product in the future. Systane® is marketed as over-the-counter tear lubricating therapy in the United States under the FDA monograph.
Primary Outcome
To evaluate the effect of OTC artificial tears on tear film stability, the evaporation rate (µl/cm2/min) will be determined with an Evaporometer for the left eye only of each patient. For each arm, the evaporation rates will be determined at baseline and at 30 minutes after installation of artificial tears. Evaporation rates in all cases will be determined under two different relative humidity (RH) conditions, RH from 25-35% and RH from 35-45%.
Interventions
- DRUG 1st visit Optive, then 2nd visit Systane
- DRUG 1st visit Systane, then 2nd visit Optive
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2007-11 |
| Est. Completion | 2009-03 |
| Phase | NA |
What the finished NCT00610480 record still lists
NCT00610480 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which 1st visit Optive, then 2nd visit Systane is the first listed.
NCT00610480 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00610480 about?
NCT00610480 is a clinical study titled "Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops". The goal of this research is to evaluate and compare the effectiveness of Systane® versus Optive™ on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the possible application for this product in the future. Systane® is marketed as over-the-counter tear lu...
What is the current status of trial NCT00610480?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2007-11. Estimated completion is 2009-03.
What interventions are being tested in trial NCT00610480?
The interventions under investigation include: 1st visit Optive, then 2nd visit Systane (DRUG), 1st visit Systane, then 2nd visit Optive (DRUG).
Who is sponsoring clinical trial NCT00610480?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00610480's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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