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NCT00283309 · ClinicalTrials.gov registry record · Phase 4
Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes
A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
NCT00283309: Clinical Trial Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
NCT00283309 is a Phase 4 study that was terminated before completion, run by University of Texas Southwestern Medical Center. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00283309, a Phase 4 study, was terminated before completion, sponsored by University of Texas Southwestern Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
Study Summary
The primary purpose is to determine if patients scheduled to receive prescription corticosteroid therapy for inflammatory illnesses who are given either memantine or riluzole pretreatment will show lesser declarative memory impairment than those receiving placebo. The exploratory purpose is to determine if patients scheduled to receive prescription corticosteroid therapy for inflammatory illnesses who are given memantine or riluzole pretreatment will show a smaller increase in manic/hypomanic symptom severity than those receiving placebo.
Interventions
- DRUG Riluzole
- DRUG Memantine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2005-11 |
| Est. Completion | 2007-04 |
| Phase | Phase 4 |
Why NCT00283309 stopped before completion
NCT00283309 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Riluzole is the first listed.
NCT00283309 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00283309 about?
NCT00283309 is a clinical study titled "Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes". The primary purpose is to determine if patients scheduled to receive prescription corticosteroid therapy for inflammatory illnesses who are given either memantine or riluzole pretreatment will show lesser declarative memory impairment than those receiving placebo. The exploratory purpose is to dete...
What is the current status of trial NCT00283309?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2005-11. Estimated completion is 2007-04.
What interventions are being tested in trial NCT00283309?
The interventions under investigation include: Riluzole (DRUG), Memantine (DRUG).
Who is sponsoring clinical trial NCT00283309?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00283309's enrollment target sits among peer trials
20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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