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NCT00461968 · ClinicalTrials.gov registry record · NA
Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both
A NA study of Cholesterol, LDL, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT00461968: Completed NA study of Cholesterol, LDL, sponsored by University of Texas Southwestern Medical Center.
NCT00461968 is a NA study of Cholesterol, LDL that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 240 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00461968, a NA study of Cholesterol, LDL, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare the percent change in LDL cholesterol induced by ezetimibe or simvastatin monotherapy and by co-administration of both agents in Black, White and Hispanic men. Ezetimibe is a drug that blocks sterol absorption and simvastatin blocks hepatic cholesterol biosynthesis. The hypothesis to be tested is that Blacks are likely to be more responsive to LDL lowering by ezetimibe than statins because Blacks have a low production of cholesterol.
Conditions Studied
Interventions
- DRUG Ezetimibe and Simvastatin
Study Locations (1)
Texas
- UT Southwestern Medical Center at Dallas - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2005-02 |
| Est. Completion | 2007-04 |
| Phase | NA |
What the finished NCT00461968 record still lists
NCT00461968 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Cholesterol, LDL appearing as the primary indexed condition, and to 1 intervention - of which Ezetimibe and Simvastatin is the first listed.
NCT00461968 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00461968 about?
NCT00461968 is a clinical study titled "Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both". The purpose of this study is to compare the percent change in LDL cholesterol induced by ezetimibe or simvastatin monotherapy and by co-administration of both agents in Black, White and Hispanic men. Ezetimibe is a drug that blocks sterol absorption and simvastatin blocks hepatic cholesterol biosynt...
What is the current status of trial NCT00461968?
This trial is currently completed. It is a NA study. The enrollment target is 240 participants. The study started on 2005-02. Estimated completion is 2007-04.
What conditions does trial NCT00461968 study?
This clinical trial studies the following conditions: Cholesterol, LDL.
What interventions are being tested in trial NCT00461968?
The interventions under investigation include: Ezetimibe and Simvastatin (DRUG).
Who is sponsoring clinical trial NCT00461968?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00461968 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00461968's enrollment target sits among peer trials
240 440th of 2000 higher than 1,542 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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