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NCT00461968 · ClinicalTrials.gov registry record · NA
Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both
A NA study of Cholesterol, LDL, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT00461968 is a NA study of Cholesterol, LDL that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 240 participants. The trial reports 1 study location across 1 state.
The verdict
NCT00461968, a NA study of Cholesterol, LDL, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare the percent change in LDL cholesterol induced by ezetimibe or simvastatin monotherapy and by co-administration of both agents in Black, White and Hispanic men. Ezetimibe is a drug that blocks sterol absorption and simvastatin blocks hepatic cholesterol biosynthesis. The hypothesis to be tested is that Blacks are likely to be more responsive to LDL lowering by ezetimibe than statins because Blacks have a low production of cholesterol.
Conditions Studied
Interventions
- DRUG Ezetimibe and Simvastatin
Study Locations (1)
Texas
- UT Southwestern Medical Center at Dallas - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2005-02 |
| Est. Completion | 2007-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00461968
The ClinicalTrials.gov registry entry for NCT00461968 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cholesterol, LDL appearing as the primary indexed condition, and to 1 intervention - of which Ezetimibe and Simvastatin is the first listed.
NCT00461968 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT00461968 about?
NCT00461968 is a clinical study titled "Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both". The purpose of this study is to compare the percent change in LDL cholesterol induced by ezetimibe or simvastatin monotherapy and by co-administration of both agents in Black, White and Hispanic men. Ezetimibe is a drug that blocks sterol absorption and simvastatin blocks hepatic cholesterol biosynt...
What is the current status of trial NCT00461968?
This trial is currently completed. It is a NA study. The enrollment target is 240 participants. The study started on 2005-02. Estimated completion is 2007-04.
What conditions does trial NCT00461968 study?
This clinical trial studies the following conditions: Cholesterol, LDL.
What interventions are being tested in trial NCT00461968?
The interventions under investigation include: Ezetimibe and Simvastatin (DRUG).
Who is sponsoring clinical trial NCT00461968?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00461968 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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