University of Pennsylvania

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count).

1,423 total trials 199 currently recruiting 982 completed early-phase tilt top decile by trial count

University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.

University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,423 total, page 6 of 29

ACTIVE NOT RECRUITING NA

Transportation Safety in Adolescence

NCT03639753

ACTIVE NOT RECRUITING

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

NCT04967365

ACTIVE NOT RECRUITING NA

Implementing PrEP for Women Who Inject Drugs

NCT05360849

ACTIVE NOT RECRUITING Phase 2

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma

NCT04680468

ACTIVE NOT RECRUITING Phase 1

huCART19-IL18 in CD19+ Cancers

NCT04684563

ACTIVE NOT RECRUITING NA

Improving Health Equity for COVID-19 Vaccination for At-risk Populations Using Online Social Networks

NCT04779827

ACTIVE NOT RECRUITING NA

CONDUIT vs. PEEK Cages

NCT06904898

ACTIVE NOT RECRUITING NA

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

NCT04245423

ACTIVE NOT RECRUITING Early Phase 1

Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls

NCT04401917

ACTIVE NOT RECRUITING NA

PennPET Explorer Scanner Evaluation

NCT04617912

ACTIVE NOT RECRUITING NA

Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana

NCT04488250

ACTIVE NOT RECRUITING Phase 4

Effects of Sitagliptin in Individuals With Genetically Decreased DPP4

NCT04323189

ACTIVE NOT RECRUITING Phase 2

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

NCT04225039

ACTIVE NOT RECRUITING

Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI

NCT04251130

ACTIVE NOT RECRUITING NA

Compressed Intermittent Theta Burst Stimulation

NCT04684706

ACTIVE NOT RECRUITING

Evaluating Cascade Communication Methods

NCT04428736

ACTIVE NOT RECRUITING NA

The Physiological Chronobiome Modified by Age, Sex and Under Evoked Conditions

NCT04225442

ACTIVE NOT RECRUITING Phase 2

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

NCT03933904

ACTIVE NOT RECRUITING NA

Clinic Navigation and Home Visits to Improve Guideline-based Care and Outcomes in Low Income Minority Adults With Asthma

NCT04023422

ACTIVE NOT RECRUITING Early Phase 1

Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT

NCT04062526

ACTIVE NOT RECRUITING Phase 1

CD4 CAR+ ZFN-modified T Cells in HIV Therapy

NCT03617198

ACTIVE NOT RECRUITING NA

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

NCT04436068

ACTIVE NOT RECRUITING NA

PROSpect: Prone and Oscillation Pediatric Clinical Trial

NCT03896763

ACTIVE NOT RECRUITING NA

Responsive Neurostimulation For Loss Of Control Eating

NCT03868670

ACTIVE NOT RECRUITING Phase 1

TEMPO Study: Trimethoprim-Sulfamethoxazole in Granulomatosis With Polyangiitis

NCT03919435

ACTIVE NOT RECRUITING

Imaging of Primary or Recurrent Breast Cancer With 18F-FluorThanatrace PET/CT

NCT03846167

ACTIVE NOT RECRUITING Phase 1

Itacitinib + Everolimus in Hodgkin Lymphoma

NCT03697408

ACTIVE NOT RECRUITING Phase 1

Lentivirally Redirected CD123 Autologous T Cells in AML

NCT03766126

ACTIVE NOT RECRUITING Phase 1

CART22 Alone or in Combination With huCART19 for ALL

NCT03620058

ACTIVE NOT RECRUITING NA

Oncology Episode Payment Model in Hawaii

NCT03523546

ACTIVE NOT RECRUITING

Hypertension Chronobiome

NCT03598894

ACTIVE NOT RECRUITING Phase 1

Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction

NCT03442413

ACTIVE NOT RECRUITING Phase 1

Up-front CART-BCMA With or Without huCART19 in High-risk Multiple Myeloma

NCT03549442

ACTIVE NOT RECRUITING

Edema and Fibrosis CMR Imaging in Cardiomyopathy

NCT03534726

ACTIVE NOT RECRUITING NA

MCI: CPAP Treatment of OSA (Memories2)

NCT03113461

ACTIVE NOT RECRUITING

Air Pollution, Asthma and Circadian Clocks

NCT03406351

ACTIVE NOT RECRUITING NA

The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial

NCT03307356

ACTIVE NOT RECRUITING

Tau PET Imaging in the NACC Study Cohort

NCT03189485

ACTIVE NOT RECRUITING Phase 4

Flu Vaccine Responses in the Setting of Melanoma Treatment

NCT03315975

ACTIVE NOT RECRUITING NA

Mapping the Shift Worker's Microbiome

NCT03221517

ACTIVE NOT RECRUITING NA

Migraine and CVD Risk in Women

NCT03081390

ACTIVE NOT RECRUITING Phase 1

CART-PSMA-TGFβRDN Cells for Castrate-Resistant Prostate Cancer

NCT03089203

ACTIVE NOT RECRUITING Early Phase 1

Adrenergic System in Islet Transplantation

NCT03079921

ACTIVE NOT RECRUITING Phase 1

Intravenous Estrogen in Kidney Transplant Study

NCT03663543

ACTIVE NOT RECRUITING Phase 1

Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT

NCT02815917

ACTIVE NOT RECRUITING Phase 1

CD22 Redirected Autologous T Cells for ALL

NCT02650414

ACTIVE NOT RECRUITING Phase 1

[18F]FLT PET/CT in Rb+ Metastatic Breast Cancer

NCT02608216

ACTIVE NOT RECRUITING Phase 1

[18F]ISO-1 Positron Emission Tomography (PET/CT) in Primary Breast Cancer

NCT02284919

ACTIVE NOT RECRUITING Phase 1

Study of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CT

NCT02379338

ACTIVE NOT RECRUITING NA

Memory Retrieval and Encoding Investigated by Neural Stimulation

NCT04286776

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Phase Distribution

PhaseTrial count
Phase 1 182
Phase 2 157
Phase 3 43
Phase 4 87

What is open in the University of Pennsylvania pipeline

199 recruiting of 1,423 indexed (14% open); 982 completed (69%).

Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.