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NCT03113461 · ClinicalTrials.gov registry record · NA
MCI: CPAP Treatment of OSA (Memories2)
A NA study of Mild Cognitive Impairment and Sleep Apnea, Obstructive, sponsored by University of Pennsylvania.
- Active
- Registry status
- NA
- Development phase
- 327
- Enrollment target
- 4
- Study locations
NCT03113461: Active NA study of Mild Cognitive Impairment and Sleep Apnea, Obstructive, sponsored by University of Pennsylvania.
NCT03113461 is a NA study of Mild Cognitive Impairment and Sleep Apnea, Obstructive that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 327 participants, below the 1,269-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (74% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03113461, a NA study of Mild Cognitive Impairment and Sleep Apnea, Obstructive, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 327 participants
- Enrollment target
- 4
- Study locations
Study Summary
The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive Impairment (MCI) as measured by cognitive testing, and brain magnetic resonance imaging (MRI) scans. Study participants will be assessed at baseline, six-month (cognitive tests only) and one-year follow-up.
Primary Outcome
incorporates both elements of memory and processing speed and correlates with executive functioning
Conditions Studied
Interventions
- DEVICE CPAP
Study Locations (4)
Missouri
- Washington University in St. Louis - St Louis
Pennsylvania
- University of Pennsylvania - Philadelphia
Texas
- University of Texas at Austin - Austin
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 327 participants |
| Start Date | 2018-01-19 |
| Est. Completion | 2025-07-01 |
| Phase | NA |
What the registry record for NCT03113461 still lists
NCT03113461 is an interventional study that assigns participants to a tested intervention. The registered 327 participants enrollment target is mid-sized for trials with a published cap, below the 1,269-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which CPAP is the first listed.
NCT03113461 reports a single indexed study location in Missouri, Pennsylvania, Texas.
Frequently Asked Questions
What is clinical trial NCT03113461 about?
NCT03113461 is a clinical study titled "MCI: CPAP Treatment of OSA (Memories2)". The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive Impairment (MCI) as measured by cognitive testing, and brain magnetic re...
What is the current status of trial NCT03113461?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 327 participants. The study started on 2018-01-19. Estimated completion is 2025-07-01.
What conditions does trial NCT03113461 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Sleep Apnea, Obstructive.
What interventions are being tested in trial NCT03113461?
The interventions under investigation include: CPAP (DEVICE).
Who is sponsoring clinical trial NCT03113461?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03113461 being conducted?
This trial has 4 study locations across Missouri, Pennsylvania, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mild Cognitive Impairment
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03113461's enrollment target sits among peer trials
327 30th of 205 higher than 176 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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