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Memory Retrieval and Encoding Investigated by Neural Stimulation
NCT04286776 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain states and behavioral measures.
Conditions Studied
Interventions
- DEVICE Direct electrical stimulation
Study Locations (11)
Pennsylvania
- Hospital of the University of Pennsylvania — Philadelphia
- Thomas Jefferson University Hospital — Philadelphia
Texas
- UT Southwestern Medical Center — Dallas
- University of Texas Health Science Center at San Antonio — San Antonio
Colorado
- University of Colorado, Denver — Aurora
Georgia
- Emory University Hospital — Atlanta
Maryland
- National Institute of Neurological Disorders and Stroke — Bethesda
Massachusetts
- Beth Israel Deaconess Medical Center — Boston
Minnesota
- Mayo Clinic — Rochester
New Hampshire
- Dartmouth-Hitchcock Medical Center — Lebanon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2014-10-12 |
| Est. Completion | 2024-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04286776
The ClinicalTrials.gov registry entry for NCT04286776 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,457 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Epilepsy Intractable appearing as the primary indexed condition, and to 1 intervention — of which Direct electrical stimulation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04286776 reports 11 study locations spanning 9 distinct geographic areas — top geographies include Pennsylvania, Texas, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04286776 about?
NCT04286776 is a clinical study titled "Memory Retrieval and Encoding Investigated by Neural Stimulation". The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain states and behavioral measures.
What is the current status of trial NCT04286776?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 800 participants. The study started on 2014-10-12. Estimated completion is 2024-12-31.
What conditions does trial NCT04286776 study?
This clinical trial studies the following conditions: Epilepsy Intractable. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04286776?
The interventions under investigation include: Direct electrical stimulation (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04286776?
This trial is sponsored by University of Pennsylvania, which has 1,457 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04286776 being conducted?
This trial has 11 study locations across Colorado, Georgia, Maryland, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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