University of Pennsylvania
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count).
University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.
University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.
Top-decile sponsor footprint
University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
1,423 total, page 5 of 29
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
NCT07132788
Fast Track to Fertility
NCT07154888
Leveraging EA8191 to Assess AI-Augmented EHR Abstraction
NCT06561230
CART123 + Ruxolitinib in Relapsed/Refractory AML
NCT06768476
Trial to Increase FEP Attendance
NCT05967195
Penn Produce Prescription and Chronic Kidney Disease Study
NCT06561412
Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension
NCT06543745
IC-CS Risk: Patient Outcomes
NCT06488092
Penn Medicine Food Market Study
NCT06283394
Reducing Fatigue With CoQ10 Supplementation in Patients With Crohn's Disease Study
NCT06419335
CD40 Agonist and PD-1 Inhibitor in HNSCC
NCT06159621
Individualized (fMRI-guided) TMS Treatment for Depression
NCT06266390
Intraoperative Echocardiography in Low-Risk CABG Surgery
NCT06154265
A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients
NCT05502861
MyStroke in Chronic Stroke
NCT06057753
A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID
NCT05931432
Tau PET Imaging in Opioid Use Disorder
NCT05651516
Randomized Clinical Trial to Improve Mobility After Hospitalization
NCT05736484
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
NCT05885594
Solriamfetol and CBT-I in Patients With Insomnia Disorder
NCT05838430
Group Preconception Care for Fertility Patients
NCT05924464
Cevostamab Following CAR T Cell Therapy for RRMM
NCT05801939
Early Metabolic Adaptations to SGLT2 Inhibition in Heart Failure
NCT05885607
The IGNITE for Kids Study on Concentrated Investment in Black Neighborhoods and Child Health and Well-Being
NCT05760001
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
NCT05828680
CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM
NCT05168423
Ibudilast for Treating Alcohol Use Disorder
NCT05414240
Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism
NCT05373537
Centralized Prescribing for Statins
NCT05537064
Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers
NCT05551754
The IGNITE Study on Concentrated Investment in Black Neighborhoods
NCT05541653
AR Ruler to Improve Safety and Clinical Workflow During PICC Placement
NCT05399875
Gamification and Medication Adherence (GAME Adherence)
NCT05326386
Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth
NCT05230004
Alveolar Ridge Preservation Following Tooth Extraction.
NCT05505084
Supporting Family Caregivers of Persons With Dementia
NCT05336344
Tau Pet Imaging in the Aging Brain Cohort Dedicated to Diversity Study
NCT05393388
Mobility and Voiding Exercises in Older Women With Urinary Incontinence (MoVEonUp)
NCT05375344
Evaluating a Strengths-based Community-grounded Intervention
NCT06701240
REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs
NCT05622721
A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD
NCT04961190
Peer Comparison Feedback to Providers to Improve Hypertension Control
NCT05160012
Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
NCT04582383
huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer
NCT05057715
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
NCT05823766
TRACK-TBI Longitudinal Biomarker Study
NCT05201833
Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System
NCT05155956
Federal Aviation Administration (FAA) National Sleep Study
NCT05035940
A Physical Activity Intervention to Promote Cognitive Health, Cardiovascular Health and Sleep in Older Latinos
NCT05030948
GFRα4 CAR T Cells in MTC Patients
NCT04877613
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 182 |
| Phase 2 | 157 |
| Phase 3 | 43 |
| Phase 4 | 87 |
Therapeutic Areas
What is open in the University of Pennsylvania pipeline
199 recruiting of 1,423 indexed (14% open); 982 completed (69%).
Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).
Top condition: Obesity (17 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.