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NCT03081390 · ClinicalTrials.gov registry record · NA

Migraine and CVD Risk in Women

A NA study of Migraine, sponsored by University of Pennsylvania.

Active
Registry status
NA
Development phase
30
Enrollment target
2
Study locations

NCT03081390: Active NA study of Migraine, sponsored by University of Pennsylvania.

NCT03081390 is a NA study of Migraine that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 30 participants, below the 358-participant average among 102 other Migraine trials with a reported enrollment target (92% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03081390, a NA study of Migraine, is active but no longer recruiting, sponsored by University of Pennsylvania.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
2
Study locations

Study Summary

The primary goal of this study is to test the effects of a high-fat, high-carbohydrate mixed meal on candidate modulators of cardiovascular disease risk (inflammation, vascular reactivity, sympathetic nervous system tone, and response to pain) in young adult women with migraine compared with healthy young women. This is study enrolling both cases (women with migraine) and controls (women without migraine), with equal numbers of normal weight and obese women in each group. Participants will undergo a telephone screening and a single day in-person study visit.

Primary Outcome

The primary study endpoint is lipopolysaccharide (LPS) area under the curve (AUC) during MMTT.

Conditions Studied

Migraine

Interventions

  • OTHER Mixed meal tolerance testing
  • OTHER Skin conductance & cold pressor test
  • OTHER Flow-mediated dilation testing

Study Locations (2)

Pennsylvania

  • University of Pennsylvania - Philadelphia
  • Children's Hospital of Philadelphia - Philadelphia

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2017-04-01
Est. Completion 2026-06-30
Phase NA
University of Pennsylvania

1,423 total trials

What the registry record for NCT03081390 still lists

NCT03081390 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 358-participant average among 102 other Migraine trials with a reported enrollment target (92% lower).

The record links to 1 condition, with Migraine appearing as the primary indexed condition, and to 3 interventions - of which Mixed meal tolerance testing is the first listed.

NCT03081390 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03081390 about?

NCT03081390 is a clinical study titled "Migraine and CVD Risk in Women". The primary goal of this study is to test the effects of a high-fat, high-carbohydrate mixed meal on candidate modulators of cardiovascular disease risk (inflammation, vascular reactivity, sympathetic nervous system tone, and response to pain) in young adult women with migraine compared with healthy...

What is the current status of trial NCT03081390?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2017-04-01. Estimated completion is 2026-06-30.

What conditions does trial NCT03081390 study?

This clinical trial studies the following conditions: Migraine.

What interventions are being tested in trial NCT03081390?

The interventions under investigation include: Mixed meal tolerance testing (OTHER), Skin conductance & cold pressor test (OTHER), Flow-mediated dilation testing (OTHER).

Who is sponsoring clinical trial NCT03081390?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03081390 being conducted?

This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Migraine

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03081390's enrollment target sits among peer trials

30 92nd of 102 higher than 8 of 102 other Migraine trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Migraine trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT03081390, the US trial registry maintained by the National Library of Medicine. NCT03081390 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.