Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03189485 · ClinicalTrials.gov registry record

Tau PET Imaging in the NACC Study Cohort

A clinical trial of MCI and Normal Controls, sponsored by University of Pennsylvania.

Active
Registry status
106
Enrollment target
1
Study location

NCT03189485 is a study of MCI and Normal Controls that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 106 participants, below the 887-participant average among 5 other MCI trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03189485, a study of MCI and Normal Controls, is active but no longer recruiting, sponsored by University of Pennsylvania.

ACTIVE NOT RECRUITING
Registry status
106 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). 18F-AV-1451 is a specialized radioactive PET imaging agent that is able to detect the presence of tau in the brain. In this study, the investigator will use the 18F-AV-1451 to capture images of tau in the brain. Findings from this study will likely provide insight into the mechanisms and distinctions of age-related cognitive decline and that of very early Alzheimer's disease.

Conditions Studied

Interventions

  • DRUG the radiotracer 18F-AV-1451

Study Locations (1)

Pennsylvania

  • UPenn - Philadelphia

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2017-11-22
Est. Completion 2026-05-31

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT03189485

The ClinicalTrials.gov registry entry for NCT03189485 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 106 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 887-participant average among 5 other MCI trials with a reported enrollment target (88% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with MCI appearing as the primary indexed condition, and to 1 intervention - of which the radiotracer 18F-AV-1451 is the first listed.

NCT03189485 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03189485 about?

NCT03189485 is a clinical study titled "Tau PET Imaging in the NACC Study Cohort". The purpose of this study is to measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). 18F-AV-1451 is a specialized radioactive PET imaging agent that is able to detect the presence of tau in the brain. In this study, the in...

What is the current status of trial NCT03189485?

This trial is currently active not recruiting. The enrollment target is 106 participants. The study started on 2017-11-22. Estimated completion is 2026-05-31.

What conditions does trial NCT03189485 study?

This clinical trial studies the following conditions: MCI, Normal Controls.

What interventions are being tested in trial NCT03189485?

The interventions under investigation include: the radiotracer 18F-AV-1451 (DRUG).

Who is sponsoring clinical trial NCT03189485?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03189485 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for MCI

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.