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NCT06441890 · ClinicalTrials.gov registry record · Phase 2

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer

A Phase 2 study of Breast Cancer and HER2-positive Breast Cancer, sponsored by University of Illinois at Chicago.

Recruiting
Registry status
Phase 2
Development phase
28
Enrollment target
1
Study location

NCT06441890 is a Phase 2 study of Breast Cancer and HER2-positive Breast Cancer that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 28 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06441890, a Phase 2 study of Breast Cancer and HER2-positive Breast Cancer, is actively recruiting participants, sponsored by University of Illinois at Chicago.

RECRUITING
Registry status
Phase 2
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

Adult men and women with early-stage, IHC/FISH-defined HER2-positive breast cancer will have a MammaPrint®/BluePrint® assay performed on the diagnostic biopsy specimen, ordered by the treating Oncologist as standard care

Interventions

  • DRUG Trastuzumab
  • DRUG Docetaxel
  • DRUG Paclitaxel
  • DRUG Nab-paclitaxel
  • DRUG Pertuzumab

Study Locations (1)

Illinois

  • University of Illinois - Chicago

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2024-12-05
Est. Completion 2028-06
Phase Phase 2

Sponsor

University of Illinois at Chicago

430 total trials

What the Registry Record Tells You About NCT06441890

The ClinicalTrials.gov registry entry for NCT06441890 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which Trastuzumab is the first listed.

NCT06441890 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT06441890 about?

NCT06441890 is a clinical study titled "BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer". Adult men and women with early-stage, IHC/FISH-defined HER2-positive breast cancer will have a MammaPrint®/BluePrint® assay performed on the diagnostic biopsy specimen, ordered by the treating Oncologist as standard care

What is the current status of trial NCT06441890?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 28 participants. The study started on 2024-12-05. Estimated completion is 2028-06.

What conditions does trial NCT06441890 study?

This clinical trial studies the following conditions: Breast Cancer, HER2-positive Breast Cancer.

What interventions are being tested in trial NCT06441890?

The interventions under investigation include: Trastuzumab (DRUG), Docetaxel (DRUG), Paclitaxel (DRUG), Nab-paclitaxel (DRUG), Pertuzumab (DRUG).

Who is sponsoring clinical trial NCT06441890?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06441890 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.