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NCT06919081 · ClinicalTrials.gov registry record · Phase 2
Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease
A Phase 2 study of Persistent Corneal Epithelial Defect and Corneal Epithelial Disorders, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT06919081 is a Phase 2 study of Persistent Corneal Epithelial Defect and Corneal Epithelial Disorders that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 24 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06919081, a Phase 2 study of Persistent Corneal Epithelial Defect and Corneal Epithelial Disorders, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
In this phase II randomized double-masked clinical trials, subjects with non-resolving corneal epithelial disease/defect (i.e., refractory to standard treatments for at least two weeks) will receive 8 weeks treatment of topical mesenchymal stem cell secretome or vehicle, with continued follow-up for up to Day 70.
Conditions Studied
Interventions
- DRUG Allogeneic Bone-Marrow Derived Mesenchymal Stromal Cells Secretome
- OTHER Vehicle Control
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-08-01 |
| Est. Completion | 2026-06-15 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06919081
The ClinicalTrials.gov registry entry for NCT06919081 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Persistent Corneal Epithelial Defect appearing as the primary indexed condition, and to 2 interventions - of which Allogeneic Bone-Marrow Derived Mesenchymal Stromal Cells Secretome is the first listed.
NCT06919081 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06919081 about?
NCT06919081 is a clinical study titled "Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease". In this phase II randomized double-masked clinical trials, subjects with non-resolving corneal epithelial disease/defect (i.e., refractory to standard treatments for at least two weeks) will receive 8 weeks treatment of topical mesenchymal stem cell secretome or vehicle, with continued follow-up for...
What is the current status of trial NCT06919081?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2025-08-01. Estimated completion is 2026-06-15.
What conditions does trial NCT06919081 study?
This clinical trial studies the following conditions: Persistent Corneal Epithelial Defect, Corneal Epithelial Disorders.
What interventions are being tested in trial NCT06919081?
The interventions under investigation include: Allogeneic Bone-Marrow Derived Mesenchymal Stromal Cells Secretome (DRUG), Vehicle Control (OTHER).
Who is sponsoring clinical trial NCT06919081?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06919081 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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