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NCT05736666 · ClinicalTrials.gov registry record · NA

Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement

A NA study of Knee Osteoarthritis and Arthroplasty Complications, sponsored by University of Illinois at Chicago.

Recruiting
Registry status
NA
Development phase
196
Enrollment target
1
Study location

NCT05736666: Recruiting NA study of Knee Osteoarthritis and Arthroplasty Complications, sponsored by University of Illinois at Chicago.

NCT05736666 is a NA study of Knee Osteoarthritis and Arthroplasty Complications that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 196 participants, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (35% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05736666, a NA study of Knee Osteoarthritis and Arthroplasty Complications, is actively recruiting participants, sponsored by University of Illinois at Chicago.

RECRUITING
Registry status
NA
Development phase
196 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training. Perturbation training involves adjusting to rapid speed changes on a treadmill. The main questions it aims to answer are: * Does perturbation training improve the way that people who are planning to have total knee replacement surgery recover after treadmill test that reproduces a trip to the front or side? * Does perturbation training reduce the incidence of preventable gait-related falls during the first year after total knee replacement? Participants will: * complete surveys about their condition and fall history and take part in testing of walking ability and balance. * have a baseline gait analysis test to measure the motion of their body during normal walking. * Be randomized into two groups. One will receive fall-prevention literature. The other will receive the same literature and then take part in a two-week treadmill perturbation training program. * be contacted every two weeks for one year, and asked questions about whether they have fallen during that time. * wear a Fitbit activity monitor on their wrist for one year. Researchers will compare the number of falls from the group that only received literature to the treatment group to see if the training group has fewer falls during the year after surgery.

Primary Outcome

post-training trunk angle at recovery step completion

Interventions

  • BEHAVIORAL Treadmill-based perturbation training
  • BEHAVIORAL Education Control

Study Locations (1)

Illinois

  • Biomechanics and Clinical Outcomes Laboratory, University of Illinois Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 196 participants
Start Date 2025-07-31
Est. Completion 2028-01
Phase NA
University of Illinois at Chicago

430 total trials

What NCT05736666 shows while recruiting

NCT05736666 is an interventional study that assigns participants to a tested intervention. The registered 196 participants enrollment target is mid-sized for trials with a published cap, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (35% lower).

The record links to 2 conditions, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Treadmill-based perturbation training is the first listed.

NCT05736666 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05736666 about?

NCT05736666 is a clinical study titled "Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement". The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training. Perturbation training involves adjusting to rapid speed changes on a treadmill. The main questions it aims to answer are: * Does perturbation t...

What is the current status of trial NCT05736666?

This trial is currently recruiting. It is a NA study. The enrollment target is 196 participants. The study started on 2025-07-31. Estimated completion is 2028-01.

What conditions does trial NCT05736666 study?

This clinical trial studies the following conditions: Knee Osteoarthritis, Arthroplasty Complications.

What interventions are being tested in trial NCT05736666?

The interventions under investigation include: Treadmill-based perturbation training (BEHAVIORAL), Education Control (BEHAVIORAL).

Who is sponsoring clinical trial NCT05736666?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05736666 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Knee Osteoarthritis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05736666's enrollment target sits among peer trials

196 25th of 101 higher than 77 of 101 other Knee Osteoarthritis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05736666, the US trial registry maintained by the National Library of Medicine. NCT05736666 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.