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NCT06823453 · ClinicalTrials.gov registry record · NA
Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction Champions
A NA study of People Who Use Opioids/People With Opioid Use Disorder (OUD) and Opioid Overdose Prevention, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- NA
- Development phase
- 600
- Enrollment target
- 1
- Study location
NCT06823453 is a NA study of People Who Use Opioids/People With Opioid Use Disorder (OUD) and Opioid Overdose Prevention that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 600 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06823453, a NA study of People Who Use Opioids/People With Opioid Use Disorder (OUD) and Opioid Overdose Prevention, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
Fatal opioid overdoses are more frequent among populations with low access to harm reduction (HR) services and with high substance use-related stigma (which is a major barrier to accessing HR services). One such population is older adults who use drugs (PWUD) on the West side of Chicago. Over 34% of Chicago's opioid-related EMS responses in 2023 were located in communities on the West side, but older adults in these communities access HR services at low rates, likely due to stigma and other barriers. To help address these barriers and increase HR service access among this population, the proposed clinical trial will evaluate a novel intervention that will recruit non-substance-using friends and family members of people who use opioids and live on the West side of Chicago, educate them on HR tools and services, and train them to become peer HR support champions. They will be asked to recruit one friend or family member who uses opioids to the study, who will also be provided with an educational training on overdose risk reduction and available HR tools and services. The intervention will then facilitate a counselor-led initial conversation between peer HR support champions and their friend or family member who uses opioids to help establish HR support, and provide all participants with naloxone and fentanyl test strip kits. This intervention will not only provide another mechanism through which PWUD can access HR tools and services, thereby reducing logistical barriers, but should also reduce stigma and increase social support by facilitating and normalizing open conversations about HR between PWUD and their non-PWUD HR support champions. Participants of a previous focus group conducted by the Investigators among West side PWUD thought this intervention would be helpful, said they would be willing to participate in it, and said they knew someone who could participate as their non-PWUD peer HR support champion. To facilitate recruitment of older adults, the Investigat
Conditions Studied
Interventions
- BEHAVIORAL Peer Harm Reduction Support Champion Intervention
Study Locations (1)
Illinois
- Community Outreach Intervention Projects (COIP) - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2025-10-28 |
| Est. Completion | 2028-09-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06823453
The ClinicalTrials.gov registry entry for NCT06823453 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with People Who Use Opioids/People With Opioid Use Disorder (OUD) appearing as the primary indexed condition, and to 1 intervention - of which Peer Harm Reduction Support Champion Intervention is the first listed.
NCT06823453 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06823453 about?
NCT06823453 is a clinical study titled "Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction Champions". Fatal opioid overdoses are more frequent among populations with low access to harm reduction (HR) services and with high substance use-related stigma (which is a major barrier to accessing HR services). One such population is older adults who use drugs (PWUD) on the West side of Chicago. Over 34% of...
What is the current status of trial NCT06823453?
This trial is currently recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2025-10-28. Estimated completion is 2028-09-01.
What conditions does trial NCT06823453 study?
This clinical trial studies the following conditions: People Who Use Opioids/People With Opioid Use Disorder (OUD), Opioid Overdose Prevention, Reduction of Substance Use-related Stigma, Non-substance-using People With a Friend or Family Member Who Uses Opioids, Peer Harm Reduction Support Champions.
What interventions are being tested in trial NCT06823453?
The interventions under investigation include: Peer Harm Reduction Support Champion Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT06823453?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06823453 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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