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NCT05427695 · ClinicalTrials.gov registry record · Phase 2
Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis
A Phase 2 study of Chronic Rhinosinusitis (Diagnosis), sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05427695 is a Phase 2 study of Chronic Rhinosinusitis (Diagnosis) that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 60 participants, below the 84-participant average among 9 other Chronic Rhinosinusitis (Diagnosis) trials with a reported enrollment target (29% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05427695, a Phase 2 study of Chronic Rhinosinusitis (Diagnosis), is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation controls in the treatment of active CRS in patients who have had prior sinus surgery based on subjective and objective outcome measures.
Conditions Studied
Interventions
- DRUG Lactobacillus sakei proBio65
- OTHER Isotonic Saline Solution
Study Locations (1)
Illinois
- University of Illinois Hospitals & Health Sciences System - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-02-05 |
| Est. Completion | 2026-07-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05427695
The ClinicalTrials.gov registry entry for NCT05427695 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 84-participant average among 9 other Chronic Rhinosinusitis (Diagnosis) trials with a reported enrollment target (29% lower). The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Rhinosinusitis (Diagnosis) appearing as the primary indexed condition, and to 2 interventions - of which Lactobacillus sakei proBio65 is the first listed.
NCT05427695 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT05427695 about?
NCT05427695 is a clinical study titled "Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis". The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation controls in the treatment of active CRS in patients who have had prior sinus surgery based on subjective and objective outcome measures.
What is the current status of trial NCT05427695?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-02-05. Estimated completion is 2026-07-30.
What conditions does trial NCT05427695 study?
This clinical trial studies the following conditions: Chronic Rhinosinusitis (Diagnosis).
What interventions are being tested in trial NCT05427695?
The interventions under investigation include: Lactobacillus sakei proBio65 (DRUG), Isotonic Saline Solution (OTHER).
Who is sponsoring clinical trial NCT05427695?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05427695 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
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