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NCT07175051 · ClinicalTrials.gov registry record · Phase 2

Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin

A Phase 2 study, sponsored by University of Illinois at Chicago.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target

NCT07175051 is a Phase 2 study that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 20 participants.

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The verdict

NCT07175051, a Phase 2 study, is actively recruiting participants, sponsored by University of Illinois at Chicago.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target

Study Summary

Sickle cell anemia (SCA) is an inherited red blood disorder. The kidneys are among the most commonly affected organ systems in SCA. The Food and Drug Administration (FDA) has approved empagliflozin as a treatment to reduce the decline of kidney function in those with kidney disease. The proposed research study aims to determine whether empagliflozin can prevent the progression of kidney dysfunction in patients with sickle cell anemia (SCA) who are at high risk of developing advanced chronic kidney disease (CKD).

Interventions

  • DRUG Empagliflozin (oral)

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-04-08
Est. Completion 2030-10
Phase Phase 2

Sponsor

University of Illinois at Chicago

430 total trials

What the Registry Record Tells You About NCT07175051

The ClinicalTrials.gov registry entry for NCT07175051 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Empagliflozin (oral) is the first listed.

NCT07175051 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07175051 about?

NCT07175051 is a clinical study titled "Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin". Sickle cell anemia (SCA) is an inherited red blood disorder. The kidneys are among the most commonly affected organ systems in SCA. The Food and Drug Administration (FDA) has approved empagliflozin as a treatment to reduce the decline of kidney function in those with kidney disease. The proposed res...

What is the current status of trial NCT07175051?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2026-04-08. Estimated completion is 2030-10.

What interventions are being tested in trial NCT07175051?

The interventions under investigation include: Empagliflozin (oral) (DRUG).

Who is sponsoring clinical trial NCT07175051?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.