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ClinicalTrials.gov 12 recruiting now early-phase tilt

Stress, Psychological: early-phase trial registry

12 of 44 indexed Stress, Psychological trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #330 of 28,707 conditions by registered trial count.

44 US clinical trials · 12 currently recruiting · #330 of 28,707 conditions by registered trial count

Stress, Psychological: 44 US clinical trials tracked, 12 recruiting.

Stress, Psychological is the subject of 44 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is University of Illinois at Chicago, running 5 of these trials.

Enrollment posture brief

Registry condition stress-psychological

OPEN 12 | RECR 27% | LATE 0 | EARLY 5 | RANK #330 | SPON 5

Nearest open-share peer: Atherosclerotic Cardiovascular Disease (27% recruiting · 22 trials)

Anorexia Nervosa54.5%Castration-Resistant Prostat38.6%Childhood Obesity31.8%Stress, Psychological (this)27%Alcohol Dependence18.2%
Open-enrollment share among volume-matched conditions near Stress, Psychological

Stress, Psychological lists 12 open slots (27% of 44 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stress, Psychological on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stress, Psychological is recruiting below its size-band peers.

    12 of 44 indexed trials (27.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stress, Psychological trials is spread across many organizations.

    University of Illinois at Chicago accounts for 5 of 44 trials (11.4%). 34 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stress, Psychological enrolment sits around 90 participants.

    Median target enrolment is 90 among the 44 trials that report a genuine target (sentinel values excluded). 25 of those (56.8%) plan for fewer than 100 participants.

  4. Stress, Psychological research is mostly interventional.

    41 interventional and 3 observational studies make up this index (93.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 24

Open and recent trials

44 total, page 1 of 1

RECRUITING 500 participants

The Nuestros Días ("Our Days") Study

University of Alabama at Birmingham

NCT06475534

RECRUITING Phase 1 200 participants

Biological and Behavioral Outcomes of Community Nature Walks

Charlotte Tate

NCT06056375

RECRUITING NA 180 participants

Foundational Programs to Combat Clinician Stress

Lancaster General Hospital

NCT07220421

RECRUITING NA 168 participants

Building Community Resilience Program

Icahn School of Medicine at Mount Sinai

NCT06771167

RECRUITING Phase 2 150 participants

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

Cedars-Sinai Medical Center

NCT05552053

RECRUITING NA 150 participants

Better Lifestyle Counseling for African American Women During Pregnancy

University of Illinois at Chicago

NCT05234125

RECRUITING NA 120 participants

Daoist Zhanzhuang and Human Flourishing

University of North Carolina, Charlotte

NCT06573034

RECRUITING NA 100 participants

Effectiveness of Relaxation Techniques

Sarah Corner

NCT04292145

RECRUITING NA 70 participants

Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families

University of Illinois at Chicago

NCT05991739

RECRUITING NA 50 participants

Testing Adapted Self-Help Plus (SH+) for Stress and Well-Being in International Students at a U.S. University

The New School

NCT07188467

RECRUITING NA 50 participants

MindWalk Intervention for Older South Asian Caregivers of People With Cognitive Disabilities (CD)

University of Illinois at Chicago

NCT06002919

RECRUITING NA 36 participants

Feasibility of the 5-Step Method in the U.S.

Villanova University

NCT06565429

ACTIVE NOT RECRUITING NA 456 participants

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

University of Michigan

NCT05451589

ACTIVE NOT RECRUITING NA 405 participants

Well-being in Students and Teachers Study

University of Illinois at Chicago

NCT06203288

ACTIVE NOT RECRUITING NA 400 participants

Biology, Identity & Opportunity Study

Northwestern University

NCT03412162

ACTIVE NOT RECRUITING NA 90 participants

Stress and Blood Pressure Management for Caregivers

Ohio State University

NCT05734638

ACTIVE NOT RECRUITING NA 70 participants

Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain

Boston Children's Hospital

NCT04488757

COMPLETED 1,506 participants

Happy Mommy! Happy Baby! Study

University of Pennsylvania

NCT01700374

COMPLETED 500 participants

Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale

Mclean Hospital

NCT06152549

COMPLETED NA 418 participants

Rural Dementia Caregiver Project

University of California, San Francisco

NCT04428112

COMPLETED NA 232 participants

Family-centered Mental Health Promotion Intervention

University of Massachusetts, Amherst

NCT04453709

COMPLETED NA 224 participants

Psychology Mobile Apps for Parents in a Pandemic

Sam Houston State University

NCT04980365

COMPLETED NA 139 participants

Healthy Eating, Activity and Reduction of Teen Stress

Kent State University

NCT04038684

COMPLETED Phase 2 109 participants

Inhaled Oxytocin and HPA Axis Reactivity

University of North Carolina, Chapel Hill

NCT03593473

COMPLETED NA 106 participants

Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV

University of Alabama at Birmingham

NCT05314088

COMPLETED NA 98 participants

A Well-being Training for Preservice Teachers

University of Wisconsin, Madison

NCT02544412

COMPLETED NA 96 participants

Mindfulness-Based College: Stage 1

Brown University

NCT03124446

COMPLETED NA 87 participants

Stress Reduction Training to Improve Sleep Quality, Stress Physiology & Cardiovascular Disease (CVD) Risk Markers

Duke University

NCT01343810

COMPLETED NA 80 participants

Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic

Duke University

NCT04632368

COMPLETED NA 66 participants

Brief Mood Enhancement Intervention

Duke University

NCT02954965

COMPLETED NA 60 participants

Wellness Coaching for Caregivers of Thoracic Transplant Candidates

Mayo Clinic

NCT04245228

COMPLETED NA 57 participants

Stress-Induced Inflammation and Reward Processing

University of California, Los Angeles

NCT03828604

COMPLETED Phase 2 53 participants

Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

National Institutes of Health Clinical Center (CC)

NCT02257853

COMPLETED NA 52 participants

Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement

University of Texas at Austin

NCT07190287

COMPLETED Phase 2 50 participants

Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress

Augusta University

NCT02431936

COMPLETED NA 45 participants

ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study

University of California, San Francisco

NCT04709549

COMPLETED NA 36 participants

Effectiveness of 10-minute Chair Massage Versus 10-minute Break to Reduce Stress and Improve Well-being

Geisinger Clinic

NCT04787107

COMPLETED NA 34 participants

A Mind-Body Intervention for Diabetes Management: A Pilot Study

Dartmouth-Hitchcock Medical Center

NCT04944264

COMPLETED NA 33 participants

Self Help Intervention to Decrease Stress

Mayo Clinic

NCT01242865

COMPLETED NA 30 participants

Digital Behavioral Interventions in Inflammatory Bowel Disease

Montefiore Medical Center

NCT04861597

COMPLETED NA 26 participants

ASD (Autism Spectrum Disorder) Telehealth for Distress Related to COVID-19

Rutgers, The State University of New Jersey

NCT04460677

COMPLETED NA 20 participants

A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women

University of Illinois at Chicago

NCT03646487

COMPLETED NA 19 participants

Vinayasa Yoga and Mood

The Miriam Hospital

NCT01719328

COMPLETED NA 16 participants

OUR Stress/ Emotion Management for Black/African American Women With Hypertension

Ohio State University

NCT04526145

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4

Named interventions

Most-linked intervention names on Stress, Psychological records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
2 trials
Standard Behavioral Weight Control (SBWC) Behavioral
1 trials
Mindfulness-Based Weight Control (MBWC) Behavioral
1 trials
Stress reduction intervention Other
1 trials
novel mindfulness-based well-being training Behavioral
1 trials
Attention and Interpretation Therapy Behavioral
1 trials
Digital mood tracking Behavioral
1 trials
Internet based cognitive behavioral therapy Behavioral
1 trials

US sites by state

Facility locations filed on Stress, Psychological trials. A trial with sites in several states counts in each.

Illinois 6 trials
North Carolina 5 trials
California 5 trials
Massachusetts 4 trials
Texas 3 trials
Pennsylvania 3 trials
Ohio 3 trials
New York 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stress, Psychological page

44 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress, Psychological condition card totals 44 registered trials; most-linked intervention Placebo; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.