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NCT06436235 · ClinicalTrials.gov registry record
Kidney Stone Inflammation
A clinical trial of Kidney Stone and Stone, Kidney, sponsored by University of Chicago.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT06436235: Recruiting study of Kidney Stone and Stone, Kidney, sponsored by University of Chicago.
NCT06436235 is a study of Kidney Stone and Stone, Kidney that is actively recruiting participants, run by University of Chicago. The registered enrollment target is 40 participants, below the 191-participant average among 28 other Kidney Stone trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06436235, a study of Kidney Stone and Stone, Kidney, is actively recruiting participants, sponsored by University of Chicago.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This observational study aims to look at the connections between kidney stones, insulin resistance, and inflammation. The researchers hypothesize that people who form calcium kidney stones and have insulin resistance may have higher levels of inflammation because they have more visceral fat (fat around the abdominal organs). The study will recruit 20 people who have had calcium kidney stones but don't have diabetes, and 20 healthy people who haven't had kidney stones. All the participants will come to the research center at the University of Chicago Medicine. Participants will have a dual-energy X-ray absorptiometry (DEXA) scan to measure their visceral fat, and give blood and urine samples. The blood will be tested for insulin resistance, inflammatory markers, and other metabolic factors. The urine will be analyzed for substances that increase kidney stone risk. The main goal is to see if the kidney stone formers with insulin resistance have more visceral fat compared to those without insulin resistance and the healthy participants. The researchers will also compare inflammatory marker levels between groups, and look at how visceral fat, inflammatory markers, insulin resistance, and urine stone risk factors are related. The findings may help explain how kidney stones are connected to metabolic conditions like diabetes and cardiovascular disease. Researchers hope this information will help identify stone formers at risk early and develop preventive treatments in the future.
Primary Outcome
Levels of visceral fat as measured by dual x-ray absorptiometry (DEXA).
Conditions Studied
Study Locations (1)
Illinois
- University of Chicago Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-06-30 |
| Est. Completion | 2026-08-01 |
What NCT06436235 shows while recruiting
NCT06436235 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 191-participant average among 28 other Kidney Stone trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Kidney Stone appearing as the primary indexed condition, and to 0 interventions.
NCT06436235 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06436235 about?
NCT06436235 is a clinical study titled "Kidney Stone Inflammation". This observational study aims to look at the connections between kidney stones, insulin resistance, and inflammation. The researchers hypothesize that people who form calcium kidney stones and have insulin resistance may have higher levels of inflammation because they have more visceral fat (fat aro...
What is the current status of trial NCT06436235?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2024-06-30. Estimated completion is 2026-08-01.
What conditions does trial NCT06436235 study?
This clinical trial studies the following conditions: Kidney Stone, Stone, Kidney.
Who is sponsoring clinical trial NCT06436235?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06436235 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Stone
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06436235's enrollment target sits among peer trials
40 18th of 28 higher than 9 of 28 other Kidney Stone trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Stone trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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