University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 16 of 16

COMPLETED NA

Improving Diabetes Care Collaboratively in the Community

NCT00359996

COMPLETED Phase 2

Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder Cancer

NCT00006105

COMPLETED Phase 2

SU5416 Compared to Dexamethasone in Treating Patients With Progressive Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00006002

COMPLETED Phase 2

Bryostatin 1 Plus Paclitaxel in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer

NCT00005849

COMPLETED Phase 1

Bcl-2 Antisense Oligodeoxynucleotide G3139 and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer

NCT00005032

TERMINATED Phase 4

Orthotopic Liver Transplantation Using a Living Donor

NCT00152607

COMPLETED Phase 2

Oxaliplatin Combined With Fluorouracil and Leucovorin in Treating Patients With Recurrent or Metastatic Cancer of the Esophagus or Stomach

NCT00004127

COMPLETED Phase 2

Oxaliplatin in Treating Patients With Metastatic Bladder Cancer

NCT00004203

COMPLETED Phase 2

Irinotecan and Cyclosporine in Treating Patients With Metastatic, Advanced or Locally Recurrent Colorectal Cancer

NCT00003950

COMPLETED NA

Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage

NCT00606905

COMPLETED Phase 2

Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer

NCT00004126

COMPLETED Phase 1

O6-benzylguanine Followed by Surgery in Treating Patients With Solid Tumors That Can Be Removed During Surgery

NCT00003766

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer

NCT00005086

COMPLETED Phase 1

Concomitant Chemoradiotherapy With Weekly Paclitaxel and Vinorelbine and Granulocyte Colony Stimulating Factor (GCSF) Support in Patients With Advanced Breast Cancer

NCT00724386

COMPLETED Phase 2

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer

NCT00004135

COMPLETED Phase 2

Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer

NCT00003557

COMPLETED Phase 2

Chemotherapy Plus Biological Therapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

NCT00004145

COMPLETED

Developing Criteria for Cortical Resections

NCT00152659

COMPLETED Phase 2

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Metastatic Melanoma

NCT00004141

COMPLETED NA

Detection of Melanoma Markers in Lymph Nodes or Peripheral Blood of Patients With Melanoma

NCT00004153

COMPLETED Phase 2

Aminocamptothecin in Treating Patients With Stomach Cancer or Cancer of the Esophagus

NCT00003192

COMPLETED Phase 2

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

NCT00000261

COMPLETED NA

Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16

NCT00000264

COMPLETED NA

Leuprolide in Treating Adults With Hypogonadotropism

NCT00004438

COMPLETED

Subjective Effects of Nitrous Oxide in Dental Patients - 17

NCT00000265

COMPLETED NA

Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12

NCT00000260

COMPLETED Phase 1

Vaccine Therapy and Interleukin-12 in Treating Patients With Metastatic Melanoma

NCT00002952

COMPLETED NA

Effects of Combined Alcohol and Nitrous Oxide Intake - 15

NCT00000263

COMPLETED Phase 1

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer or Primary Peritoneal Cancer

NCT00003136

COMPLETED Phase 1

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer

NCT00002939

COMPLETED NA

Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14

NCT00000262

COMPLETED NA

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11

NCT00000259

COMPLETED Phase 1

Vinorelbine and Paclitaxel Plus Radiation Therapy in Treating Patients With Advanced Cancer Arising in the Pelvis

NCT00002949

COMPLETED Phase 2

Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer

NCT00002951

COMPLETED NA

Role of Instructions in Nitrous Oxide Effects and Choice - 10

NCT00000258

COMPLETED NA

Effects of Alcohol History on Effects of Nitrous Oxide - 9

NCT00000257

COMPLETED NA

Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8

NCT00000256

COMPLETED Phase 2

Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7

NCT00000255

COMPLETED Phase 2

Isoflurane at Subanesthetic Concentrations - 6

NCT00000254

COMPLETED NA

Effects of Nitrous Oxide: A Dose-Response Analysis - 5

NCT00000253

COMPLETED NA

Leuprolide in Determining the Cause of Gonadotropin Deficiency

NCT00004426

COMPLETED Phase 2

Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4

NCT00000252

COMPLETED Phase 2

Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3

NCT00000251

COMPLETED Phase 2

Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

NCT00000250

COMPLETED Phase 2

Effects of Subanesthetic Concentrations of Nitrous Oxide - 1

NCT00000249

COMPLETED

Chicago Childhood Diabetes Registry

NCT00204009

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Chicago pipeline card: 796 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.