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NCT00000254 · ClinicalTrials.gov registry record · Phase 2
Isoflurane at Subanesthetic Concentrations - 6
A Phase 2 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT00000254: Completed Phase 2 study, sponsored by University of Chicago.
NCT00000254 is a Phase 2 study that has completed, run by University of Chicago. The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000254, a Phase 2 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To test the hypothesis that isoflurane at subanesthetic concentrations does not reduce cold-water immersion pain in healthy volunteers.
Primary Outcome
Effects of inhaled isoflurane on pain from immersion of subject's arm in ice cold water. Nitrous oxide (40%) was used as a positive control to confirm sensitivity of the pain assay.
Interventions
- OTHER Sham comparator
- DRUG 0.2% isoflurane
- DRUG 0.4% isoflurane
- DRUG 40% Nitrous oxide
- DRUG 0.6% isoflurane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 1995-01 |
| Est. Completion | 1995-09 |
| Phase | Phase 2 |
What the finished NCT00000254 record still lists
NCT00000254 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 5 interventions - of which Sham comparator is the first listed.
NCT00000254 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000254 about?
NCT00000254 is a clinical study titled "Isoflurane at Subanesthetic Concentrations - 6". The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To test the hypothesis that isoflurane at...
What is the current status of trial NCT00000254?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 1995-01. Estimated completion is 1995-09.
What interventions are being tested in trial NCT00000254?
The interventions under investigation include: Sham comparator (OTHER), 0.2% isoflurane (DRUG), 0.4% isoflurane (DRUG), 40% Nitrous oxide (DRUG), 0.6% isoflurane (DRUG).
Who is sponsoring clinical trial NCT00000254?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000254's enrollment target sits among peer trials
10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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