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NCT00000259 · ClinicalTrials.gov registry record · NA
Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11
A NA study, sponsored by University of Chicago.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT00000259: Completed NA study, sponsored by University of Chicago.
NCT00000259 is a NA study that has completed, run by University of Chicago. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000259, a NA study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and psychomotor performance.
Primary Outcome
Subjects underwent a 3 min cold immersion test at 30 min of inhalation and then provided response to pain intensity questionnaire
Interventions
- OTHER Placebo
- DRUG 15 % Nitrous oxide
- DRUG 0.3 % Sevoflurane
- DRUG 30% Nitrous oxide
- DRUG 0.6% Sevoflurane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 1996-08 |
| Est. Completion | 1997-11 |
| Phase | NA |
What the finished NCT00000259 record still lists
NCT00000259 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT00000259 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000259 about?
NCT00000259 is a clinical study titled "Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11". The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiate...
What is the current status of trial NCT00000259?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 1996-08. Estimated completion is 1997-11.
What interventions are being tested in trial NCT00000259?
The interventions under investigation include: Placebo (OTHER), 15 % Nitrous oxide (DRUG), 0.3 % Sevoflurane (DRUG), 30% Nitrous oxide (DRUG), 0.6% Sevoflurane (DRUG).
Who is sponsoring clinical trial NCT00000259?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000259's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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