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NCT00000253 · ClinicalTrials.gov registry record · NA

Effects of Nitrous Oxide: A Dose-Response Analysis - 5

A NA study, sponsored by University of Chicago.

Completed
Registry status
NA
Development phase
16
Enrollment target

NCT00000253: Completed NA study, sponsored by University of Chicago.

NCT00000253 is a NA study that has completed, run by University of Chicago. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000253, a NA study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
NA
Development phase
16 participants
Enrollment target

Study Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine the subjective, psychomotor, and reinforcing effects of nitrous oxide in healthy volunteers. This is a dose-response analysis.

Primary Outcome

Subjects underwent 4 sessions consisting of 2 sample tests (inhaling placebo and inhaling varying doses of N2O), then choosing which inhalant they wanted for a choice test. The subject \& the technician administering the inhalant were blinded. During each intervention and each session, subjects underwent psychomotor testing.

Interventions

  • DRUG 40% N2O
  • DRUG 20% N2O
  • DRUG 10% N2O
  • DRUG 30% N2O

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 1994-11
Est. Completion 1996-03
Phase NA
University of Chicago

796 total trials

What the finished NCT00000253 record still lists

NCT00000253 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 4 interventions - of which 40% N2O is the first listed.

NCT00000253 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000253 about?

NCT00000253 is a clinical study titled "Effects of Nitrous Oxide: A Dose-Response Analysis - 5". The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine the subjective, psychomotor, a...

What is the current status of trial NCT00000253?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 1994-11. Estimated completion is 1996-03.

What interventions are being tested in trial NCT00000253?

The interventions under investigation include: 40% N2O (DRUG), 20% N2O (DRUG), 10% N2O (DRUG), 30% N2O (DRUG).

Who is sponsoring clinical trial NCT00000253?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000253's enrollment target sits among peer trials

16 1871st of 2000 higher than 120 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000253, the US trial registry maintained by the National Library of Medicine. NCT00000253 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.