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NCT00000257 · ClinicalTrials.gov registry record · NA

Effects of Alcohol History on Effects of Nitrous Oxide - 9

A NA study, sponsored by University of Chicago.

Completed
Registry status
NA
Development phase
19
Enrollment target

NCT00000257: Completed NA study, sponsored by University of Chicago.

NCT00000257 is a NA study that has completed, run by University of Chicago. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000257, a NA study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
NA
Development phase
19 participants
Enrollment target

Study Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To determine effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers.

Primary Outcome

Two subject groups (light drinkers vs moderate drinkers) were asked to inhale a given conc of N2O and inhale a placebo, then choose for a third inhalation. The subject \& the technician administering the inhalant were blinded. Testing was done at each dose.

Interventions

  • DRUG 0% N2O and 10% N2O
  • DRUG 0% N2O and 20% N2O
  • DRUG 0% N2O and 30% N2O
  • DRUG 0% N2O and 40% N2O

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 1995-09
Est. Completion 1997-04
Phase NA
University of Chicago

796 total trials

What the finished NCT00000257 record still lists

NCT00000257 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 4 interventions - of which 0% N2O and 10% N2O is the first listed.

NCT00000257 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000257 about?

NCT00000257 is a clinical study titled "Effects of Alcohol History on Effects of Nitrous Oxide - 9". The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiate...

What is the current status of trial NCT00000257?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 1995-09. Estimated completion is 1997-04.

What interventions are being tested in trial NCT00000257?

The interventions under investigation include: 0% N2O and 10% N2O (DRUG), 0% N2O and 20% N2O (DRUG), 0% N2O and 30% N2O (DRUG), 0% N2O and 40% N2O (DRUG).

Who is sponsoring clinical trial NCT00000257?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000257's enrollment target sits among peer trials

19 1861st of 2000 higher than 138 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000257, the US trial registry maintained by the National Library of Medicine. NCT00000257 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.