University of California, Irvine
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, University of California, Irvine sits in the top decile of US sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count).
University of California, Irvine: 368 sponsored US clinical trials, 74 recruiting.
University of California, Irvine sponsors 368 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 228 completed. 27 of these trials are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cancer, with 6 trials.
Top-decile sponsor footprint
University of California, Irvine ranks in the top decile of sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
228 of 258 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
368 total, page 2 of 8
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
NCT05497531
Imaging-based Assessment of Oral Biofilm and Gingival Health
NCT05470023
Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
NCT05524584
Treatment of Meniere's Disease With Migraine Medications
NCT05582837
Using Nicotine to Reverse Age-related Auditory Processing Deficits
NCT04971954
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
NCT05123365
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
NCT05169814
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
NCT05603650
Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas
NCT04920032
Dementia Family Caregiver Study
NCT04894006
Spectroscopic Evaluation of Middle Ear Infection
NCT04812093
Exercise in Child Health
NCT05359991
Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
NCT04861103
Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma
NCT04472767
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
NCT03977207
Treatment of Tinnitus With Migraine Medications
NCT04404439
Biomarker Exploration in Aging, Cognition and Neurodegeneration
NCT03860857
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
NCT01771718
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
NCT01484730
Characterization of Familial Myopathy and Paget Disease of Bone
NCT01166854
Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential
NCT01166893
Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
NCT00842283
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
NCT01353430
Effect of Electro-Acupuncture on Blood Pressure
NCT00932139
Management of Acute Tinnitus With Migraine Medications
NCT06799169
Scientific Information and Beliefs About Psychological Therapy
NCT06825000
Relaxation Music for Chronic Pain
NCT06993272
Health Questionnaire Study
NCT06956378
Youth Nominated Support Team
NCT05558332
Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
NCT06340906
Addressing Financial and Social Needs Among Patients With Cancer
NCT06430840
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
NCT06353269
Caffeine Use in the Management of Preterm Infants
NCT06327152
Empowering Hispanic Patients' Lung Cancer Screening Uptake (Empower Latinx)
NCT06225414
Pelvic Floor Physical Therapy to Reduce Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
NCT06209307
Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients
NCT05979103
Jazz Music and Mindfulness for Chronic Pain
NCT05979012
Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
NCT05641519
Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma
NCT05488366
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors
NCT05334329
Determinants of the Effectiveness of Robot-assisted Hand Movement Training
NCT04818073
Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors
NCT05283577
Sporadic Inclusion Body Myositis Natural History Study
NCT05046821
Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy
NCT04868773
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder
NCT04712981
Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis
NCT04762953
Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
NCT04737616
CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia
NCT04231851
Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
NCT04164979
Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ
NCT03935685
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 46 |
| Phase 2 | 46 |
| Phase 3 | 6 |
| Phase 4 | 21 |
Therapeutic Areas
What is open in the University of California, Irvine pipeline
74 recruiting of 368 indexed (20% open); 228 completed (62%).
Phase mix: 27 late (III/IV) vs 92 early (I/II) (early-phase heavy).
Top condition: Cancer (6 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
University of California, Irvine: open-pipeline peers nationwide
Peers matched on 368 registered trials and 20% open enrollment, not the therapeutic-area sidebar.
University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 368 trials (± recruiting share)
- Northwell Health · 370 trials · 22% recruiting
- UNC Lineberger Comprehensive Cancer Center · 366 trials · 22% recruiting
- Roswell Park Cancer Institute · 365 trials · 16% recruiting
- New York State Psychiatric Institute · 364 trials · 3% recruiting
Sponsors near 20% open enrollment (± trial volume)
- University of Miami · 20% recruiting · 721 trials
- Endeavor Health · 20% recruiting · 94 trials
- Acera Surgical · 20% recruiting · 5 trials
- Align Technology · 20% recruiting · 5 trials
Related
What to do with this University of California, Irvine page
368 registered trials is a research-attention snapshot, not an endorsement of University of California, Irvine or any single study.
- 74 of University of California, Irvine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Cancer is the condition University of California, Irvine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Cancer trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
University of California, Irvine pipeline card: 368 registered trials from official public datasets.Report a data error.