Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04737616 · ClinicalTrials.gov registry record · NA
Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
A NA study of Genitourinary Syndrome of Menopause, sponsored by University of California, Irvine.
- Active
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT04737616: Active NA study of Genitourinary Syndrome of Menopause, sponsored by University of California, Irvine.
NCT04737616 is a NA study of Genitourinary Syndrome of Menopause that is active but no longer recruiting, run by University of California, Irvine. The registered enrollment target is 90 participants, below the 372-participant average among 6 other Genitourinary Syndrome of Menopause trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04737616, a NA study of Genitourinary Syndrome of Menopause, is active but no longer recruiting, sponsored by University of California, Irvine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
We have recently developed and optimized a vaginal Optical Coherence tomography/angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the vaginal epithelium, blood vessels, and lamina propria. The primary focus of this study is establishing the Optical Coherence Tomography system's capability of capturing vaginal changes that occur before and after menopause, as well as before and after treatment with fractional-CO2 laser therapy. There are two aims of this study. Aim 1: 1\. To determine the feasibility and sensitivity of the integrated optical coherence endoscope to assess vaginal tissue integrity in pre, peri and postmenopausal women. Aim 2: To optically visualize the effects of fractional-CO2 laser treatment on vaginal tissue over the course of C02 vaginal laser therapy.
Primary Outcome
Vaginal epithelium thickness measured with the OCT.
Conditions Studied
Interventions
- DEVICE OCT
- DEVICE CO2 laser
Study Locations (1)
California
- Beckman Laser Institute and Medical Clinic - Irvine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2020-07-16 |
| Est. Completion | 2026-07 |
| Phase | NA |
What the registry record for NCT04737616 still lists
NCT04737616 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 372-participant average among 6 other Genitourinary Syndrome of Menopause trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Genitourinary Syndrome of Menopause appearing as the primary indexed condition, and to 2 interventions - of which OCT is the first listed.
NCT04737616 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04737616 about?
NCT04737616 is a clinical study titled "Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy". We have recently developed and optimized a vaginal Optical Coherence tomography/angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the vaginal epithelium, blood vessels, and lamina propria. The primary focus of this study is establishing the Optical Cohe...
What is the current status of trial NCT04737616?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2020-07-16. Estimated completion is 2026-07.
What conditions does trial NCT04737616 study?
This clinical trial studies the following conditions: Genitourinary Syndrome of Menopause.
What interventions are being tested in trial NCT04737616?
The interventions under investigation include: OCT (DEVICE), CO2 laser (DEVICE).
Who is sponsoring clinical trial NCT04737616?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04737616 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Genitourinary Syndrome of Menopause
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Vaginal Changes After CO2 Laser
RECRUITING · NA
-
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
RECRUITING · NA
-
Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause
RECRUITING · NA
-
PRP Injections for Genitourinary Syndrome of Menopause
ACTIVE NOT RECRUITING · NA
-
MonaLisa Touch Randomized Double-Blind Placebo Controlled Study
COMPLETED · NA
-
A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause
ACTIVE NOT RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02521311 · 90 participants · Phase 2
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
- NCT02939573 · 90 participants · Phase 2
A Randomized Multicenter Study for Isolated Skin Vasculitis
- NCT03128879 · 90 participants · Phase 2
Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL
- NCT03184038 · 90 participants · NA
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI