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NCT05123365 · ClinicalTrials.gov registry record · Phase 1

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

A Phase 1 study of Myelofibrosis and Myeloproliferative Neoplasm, sponsored by University of California, Irvine.

Recruiting
Registry status
Phase 1
Development phase
27
Enrollment target
2
Study locations

NCT05123365 is a Phase 1 study of Myelofibrosis and Myeloproliferative Neoplasm that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 27 participants, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (86% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT05123365, a Phase 1 study of Myelofibrosis and Myeloproliferative Neoplasm, is actively recruiting participants, sponsored by University of California, Irvine.

RECRUITING
Registry status
Phase 1
Development phase
27 participants
Enrollment target
2
Study locations

Study Summary

This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).

Conditions Studied

Myelofibrosis Myeloproliferative Neoplasm Polycythemia Vera Essential Thrombocythemia MPN

Interventions

  • DRUG N-Acetylcysteine

Study Locations (2)

California

  • University of California, Irvine - Irvine
  • Chao Family Comprehensive Cancer Center, University of California, Irvine - Orange

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2022-01-03
Est. Completion 2026-11-15
Phase Phase 1

Sponsor

University of California, Irvine

368 total trials

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What the Registry Record Tells You About NCT05123365

The ClinicalTrials.gov registry entry for NCT05123365 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (86% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Myelofibrosis appearing as the primary indexed condition, and to 1 intervention - of which N-Acetylcysteine is the first listed.

NCT05123365 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05123365 about?

NCT05123365 is a clinical study titled "An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms". This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).

What is the current status of trial NCT05123365?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2022-01-03. Estimated completion is 2026-11-15.

What conditions does trial NCT05123365 study?

This clinical trial studies the following conditions: Myelofibrosis, Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, MPN.

What interventions are being tested in trial NCT05123365?

The interventions under investigation include: N-Acetylcysteine (DRUG).

Who is sponsoring clinical trial NCT05123365?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05123365 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.