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NCT04920032 · ClinicalTrials.gov registry record · Phase 1
Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas
A Phase 1 study of Colorectal Cancer and Colon Adenocarcinoma, sponsored by University of California, Irvine.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT04920032 is a Phase 1 study of Colorectal Cancer and Colon Adenocarcinoma that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 22 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04920032, a Phase 1 study of Colorectal Cancer and Colon Adenocarcinoma, is actively recruiting participants, sponsored by University of California, Irvine.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a phase 1b, prospective, single arm, non-randomized, open-label clinical trial determining the efficacy of adjuvant trifluridine and tipiracil (TAS-102) in combination with irinotecan in patients with ctDNA positive colon adenocarcinoma.
Conditions Studied
Interventions
- DRUG Irinotecan
- DRUG TAS-102
- COMBINATION_PRODUCT Standard Treatment
- DIAGNOSTIC_TEST Signatera MRD ctDNA Assay
Study Locations (1)
California
- Chao Family Comprehensive Cancer Center, University of California, Irvine - Orange
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2021-08-26 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04920032
The ClinicalTrials.gov registry entry for NCT04920032 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 4 interventions - of which Irinotecan is the first listed.
NCT04920032 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT04920032 about?
NCT04920032 is a clinical study titled "Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas". This is a phase 1b, prospective, single arm, non-randomized, open-label clinical trial determining the efficacy of adjuvant trifluridine and tipiracil (TAS-102) in combination with irinotecan in patients with ctDNA positive colon adenocarcinoma.
What is the current status of trial NCT04920032?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2021-08-26. Estimated completion is 2026-12-31.
What conditions does trial NCT04920032 study?
This clinical trial studies the following conditions: Colorectal Cancer, Colon Adenocarcinoma.
What interventions are being tested in trial NCT04920032?
The interventions under investigation include: Irinotecan (DRUG), TAS-102 (DRUG), Standard Treatment (COMBINATION_PRODUCT), Signatera MRD ctDNA Assay (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04920032?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04920032 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.