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NCT05169814 · ClinicalTrials.gov registry record · Early Phase 1
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
A Early Phase 1 study of Wound Heal and Open Wound, sponsored by University of California, Irvine.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05169814: Recruiting Early Phase 1 study of Wound Heal and Open Wound, sponsored by University of California, Irvine.
NCT05169814 is a Early Phase 1 study of Wound Heal and Open Wound that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 40 participants, below the 118-participant average among 23 other Wound Heal trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05169814, a Early Phase 1 study of Wound Heal and Open Wound, is actively recruiting participants, sponsored by University of California, Irvine.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.
Primary Outcome
Near Infrared Spectroscopy Imaging (NIRS) (KENT SnapShot https://www.kentimaging.com/product/) will be used to assess wound oxygenation saturation levels prior to the MNB or normal saline application. This will provide the investigators with a baseline oxygen saturation measurement. The NIRS KENT SnapShot is an FDA approved non-contact-based imaging modality used to assess wound/tissue oxygenation in the clinical setting and is currently available in the investigators' research laboratory.
Conditions Studied
Interventions
- DRUG Micro/nanobubble (MNB) - Irrigation
- OTHER 0.9% Normal Saline - Irrigation
- DRUG Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi)
- OTHER 0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi)
Study Locations (1)
California
- UCI Medical Center - Orange
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-10-09 |
| Est. Completion | 2027-06-01 |
| Phase | Early Phase 1 |
What NCT05169814 shows while recruiting
NCT05169814 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 118-participant average among 23 other Wound Heal trials with a reported enrollment target (66% lower).
The record links to 2 conditions, with Wound Heal appearing as the primary indexed condition, and to 4 interventions - of which Micro/nanobubble (MNB) - Irrigation is the first listed.
NCT05169814 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05169814 about?
NCT05169814 is a clinical study titled "Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds". The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.
What is the current status of trial NCT05169814?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2021-10-09. Estimated completion is 2027-06-01.
What conditions does trial NCT05169814 study?
This clinical trial studies the following conditions: Wound Heal, Open Wound.
What interventions are being tested in trial NCT05169814?
The interventions under investigation include: Micro/nanobubble (MNB) - Irrigation (DRUG), 0.9% Normal Saline - Irrigation (OTHER), Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi) (DRUG), 0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi) (OTHER).
Who is sponsoring clinical trial NCT05169814?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05169814 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05169814's enrollment target sits among peer trials
40 16th of 23 higher than 7 of 23 other Wound Heal trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Wound Heal trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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