University of California, Irvine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of California, Irvine sits in the top decile of US sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count).

368 total trials 74 currently recruiting 228 completed early-phase tilt top decile by trial count

University of California, Irvine: 368 sponsored US clinical trials, 74 recruiting.

University of California, Irvine sponsors 368 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 228 completed. 27 of these trials are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cancer, with 6 trials.

Top-decile sponsor footprint

University of California, Irvine ranks in the top decile of sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

228 of 258 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

368 total, page 3 of 8

ACTIVE NOT RECRUITING NA

Baby's First Years

NCT03593356

ACTIVE NOT RECRUITING NA

Acoustic and Electrical Stimulation for the Treatment of Tinnitus

NCT03511807

ACTIVE NOT RECRUITING Phase 2

Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab

NCT02436993

ACTIVE NOT RECRUITING

Skin Imaging With Technologies in Development

NCT00764920

NOT YET RECRUITING NA

Patient Satisfaction and Cosmetic Outcomes in Adhesive Strip Versus Suture Repair for Simple Facial Lacerations

NCT06550999

NOT YET RECRUITING Phase 2

Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma

NCT07527325

NOT YET RECRUITING Phase 4

Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound

NCT07167862

NOT YET RECRUITING Phase 2

Utilization of Flotufolastat 18F PET for Post-Focal Therapy Prostate Cancer Evaluation

NCT07568756

NOT YET RECRUITING NA

Musical Mindfulness for Pain in the ED Waiting Room

NCT07391891

NOT YET RECRUITING NA

Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD

NCT07178821

COMPLETED NA

Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes

NCT06518798

COMPLETED NA

Empowering Patients' Lung Cancer Screening Uptake

NCT06000683

COMPLETED NA

Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke

NCT05880940

TERMINATED Phase 2

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

NCT03066739

COMPLETED

Patient Observational Pain and Activity Survey (POPAS) Study Using RS-4i Sequential Stimulator With Intersperse Technology in Axial Spine and Peripheral Joint Pain

NCT05478265

COMPLETED Early Phase 1

A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm

NCT05555342

COMPLETED NA

SSIs for Mental Health and Loneliness

NCT05687162

COMPLETED NA

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

NCT05658757

COMPLETED NA

The Heart of the Community Study

NCT05560893

COMPLETED Phase 4

Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial

NCT05308979

COMPLETED NA

Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness

NCT05897580

COMPLETED Phase 4

Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial

NCT05321121

COMPLETED NA

Animal Assisted Intervention With Dogs for Children With ADHD

NCT05102344

COMPLETED NA

Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer

NCT06622252

COMPLETED NA

HOPE Intervention for COVID-19

NCT04376515

COMPLETED NA

Emotion-Diet Interactions in Pregnancy

NCT04430439

COMPLETED NA

Effect of Combined Red and Near Infrared Light-emitting Diode (LED) Therapy on Tissue Regeneration Post Laser Treatment

NCT04834817

COMPLETED Early Phase 1

Characterizing Skin Microbiome Change in Atopic Dermatitis

NCT04800185

COMPLETED NA

Evaluation of a Crowd-Powered Web Platform for Depression and Anxiety

NCT04226742

COMPLETED Phase 2

Remotely Administered Diet Intervention to Impact Symptom Burden in Myeloproliferative Neoplasm

NCT04744974

COMPLETED NA

Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA

NCT05468398

COMPLETED Phase 1

Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia

NCT04512105

TERMINATED Phase 4

Comparison of Potassium Binders in the ER

NCT04585542

COMPLETED NA

Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults

NCT04513899

COMPLETED NA

Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence

NCT04585594

COMPLETED NA

Young Adult Latino Testicular Cancer Survivors: a Pilot Study of Goal-Focused Emotion Regulation Therapy (GET)

NCT07615998

TERMINATED Phase 2

Neo-Adjuvant Abemaciclib With Fulvestrant in Patients With ER/PR +HER Negative Breast Cancer

NCT04305236

COMPLETED NA

BCI-FES Therapy for Stroke Rehabilitation

NCT04279067

COMPLETED NA

Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial

NCT04182126

TERMINATED NA

Skin Imaging to Inform Laser Treatments

NCT04336163

COMPLETED Phase 1

TAS-102 and Irinotecan in 2L+ Gastric and Gastroesophageal Adenocarcinoma

NCT04074343

COMPLETED NA

Treating Pain in Children With Cancer: Pain Buddy

NCT03384134

COMPLETED NA

Treatment of Tinnitus Using a Web-based Sound and Cognitive Behavioral Therapy

NCT02438891

COMPLETED NA

Study Of Drinks With Artificial Sweeteners in People With Type 2 Diabetes

NCT03944616

TERMINATED Phase 3

Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic Procedures

NCT04849858

COMPLETED Phase 1

Combined Focused Ultrasound and Calcium Hydroxylapatitie Filler for Skin Laxity and Volume Restoration

NCT04176068

COMPLETED NA

An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)

NCT03730259

TERMINATED NA

Sensory Enrichment for Older Adults

NCT03914989

COMPLETED NA

Nurse-Led Community Health Worker Adherence Model in 3HP Delivery Among Homeless Adults at Risk for TB Infection and HIV

NCT03702049

COMPLETED NA

The Effects of a Mobile Health Intervention and Health Coach Text Messaging on Cardiovascular Risk of Older Adults

NCT03720327

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Phase Distribution

PhaseTrial count
Phase 1 46
Phase 2 46
Phase 3 6
Phase 4 21

What is open in the University of California, Irvine pipeline

74 recruiting of 368 indexed (20% open); 228 completed (62%).

Phase mix: 27 late (III/IV) vs 92 early (I/II) (early-phase heavy).

Top condition: Cancer (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of California, Irvine: open-pipeline peers nationwide

Peers matched on 368 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share University of California, IrvineNorthwell HealthUNC Lineberger Comprehensive Cancer CenterRoswell Park Cancer InstituteNew York State Psychiatric InstituteUniversity of MiamiEndeavor HealthAcera SurgicalAlign Technology
University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 368 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of California, Irvine page

368 registered trials is a research-attention snapshot, not an endorsement of University of California, Irvine or any single study.

  • 74 of University of California, Irvine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Cancer is the condition University of California, Irvine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of California, Irvine pipeline card: 368 registered trials from official public datasets.Report a data error.