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NCT04868773 · ClinicalTrials.gov registry record · Phase 1

Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy

A Phase 1 study of Colorectal Cancer and Metastatic Cancer, sponsored by University of California, Irvine.

Active
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT04868773 is a Phase 1 study of Colorectal Cancer and Metastatic Cancer that is active but no longer recruiting, run by University of California, Irvine. The registered enrollment target is 12 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04868773, a Phase 1 study of Colorectal Cancer and Metastatic Cancer, is active but no longer recruiting, sponsored by University of California, Irvine.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This is a phase I clinical trial assessing the safety and recommended phase II dose of cabozantinib in combination with trifluridine/tipiracil (TAS102) in patients with metastatic colorectal carcinoma (mCRC).

Interventions

  • DRUG Cabozantinib
  • DRUG TAS-102

Study Locations (1)

California

  • Chao Family Comprehensive Cancer Center, University of California, Irvine - Orange

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2021-07-16
Est. Completion 2026-02
Phase Phase 1

Sponsor

University of California, Irvine

368 total trials

What the Registry Record Tells You About NCT04868773

The ClinicalTrials.gov registry entry for NCT04868773 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Cabozantinib is the first listed.

NCT04868773 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04868773 about?

NCT04868773 is a clinical study titled "Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy". This is a phase I clinical trial assessing the safety and recommended phase II dose of cabozantinib in combination with trifluridine/tipiracil (TAS102) in patients with metastatic colorectal carcinoma (mCRC).

What is the current status of trial NCT04868773?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2021-07-16. Estimated completion is 2026-02.

What conditions does trial NCT04868773 study?

This clinical trial studies the following conditions: Colorectal Cancer, Metastatic Cancer, Colorectal Carcinoma, CRC.

What interventions are being tested in trial NCT04868773?

The interventions under investigation include: Cabozantinib (DRUG), TAS-102 (DRUG).

Who is sponsoring clinical trial NCT04868773?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04868773 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.