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NCT05603650 · ClinicalTrials.gov registry record · NA
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
A NA study of Microbial Colonization and Viral Infection, sponsored by University of California, Irvine.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT05603650: Recruiting NA study of Microbial Colonization and Viral Infection, sponsored by University of California, Irvine.
NCT05603650 is a NA study of Microbial Colonization and Viral Infection that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 200 participants, below the 12,645-participant average among 20 other Microbial Colonization trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05603650, a NA study of Microbial Colonization and Viral Infection, is actively recruiting participants, sponsored by University of California, Irvine.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwash, or water. The overall duration of the study will be approximately 180 days and will include approximately 5 visits and 15-30 minutes for each visit with a total of approximately 2.5 hours of your time. Additionally, fecal matter will also be collected in some subjects using a commercial collection kit.
Primary Outcome
total bacterial load as determined from oral swabs and collected fecal samples, followed by subsequent standard mRNA analysis using RT-PCR
Conditions Studied
Interventions
- OTHER Lumineux Oral Essentials rinse
- OTHER Listerine rinse
Study Locations (1)
California
- Beckman Laser Institute and Medical Clinic - Irvine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT05603650 shows while recruiting
NCT05603650 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 12,645-participant average among 20 other Microbial Colonization trials with a reported enrollment target (98% lower).
The record links to 4 conditions, with Microbial Colonization appearing as the primary indexed condition, and to 2 interventions - of which Lumineux Oral Essentials rinse is the first listed.
NCT05603650 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05603650 about?
NCT05603650 is a clinical study titled "Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract". The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwas...
What is the current status of trial NCT05603650?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2021-09-01. Estimated completion is 2027-12.
What conditions does trial NCT05603650 study?
This clinical trial studies the following conditions: Microbial Colonization, Viral Infection, Oral Bacterial Infection, Oral Infection.
What interventions are being tested in trial NCT05603650?
The interventions under investigation include: Lumineux Oral Essentials rinse (OTHER), Listerine rinse (OTHER).
Who is sponsoring clinical trial NCT05603650?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05603650 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Microbial Colonization
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05603650's enrollment target sits among peer trials
200 5th of 20 higher than 16 of 20 other Microbial Colonization trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Microbial Colonization trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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