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NCT03731221 · ClinicalTrials.gov registry record · Early Phase 1
Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine
A Early Phase 1 study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 196
- Enrollment target
NCT03731221: Completed Early Phase 1 study, sponsored by The Cleveland Clinic.
NCT03731221 is a Early Phase 1 study that has completed, run by The Cleveland Clinic. The registered enrollment target is 196 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (270% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03731221, a Early Phase 1 study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 196 participants
- Enrollment target
Study Summary
Patients will be randomized the day of surgery upon presentation to the operating room to either a treatment group (PECSII/SAP blocks with bupivacaine HCl plus liposomal bupivacaine) or a control group (PECSII/SAP blocks with bupivacaine HCl plus preservative free normal saline) using secure web-based randomization. Assignments will be based on computer-generated code. Clinicians will not be blinded to the intervention, but all outcomes will be assessed by research personnel who are blinded to the group assignment.
Primary Outcome
The overall benefit of analgesia score (OBAS) is based on 7 questions and ranges from 0 to 28 points
Interventions
- DRUG Bupi HCI and lipo bupi
- DRUG Bupi HCI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 196 participants |
| Start Date | 2018-11-01 |
| Est. Completion | 2024-09-19 |
| Phase | Early Phase 1 |
What the finished NCT03731221 record still lists
NCT03731221 is an interventional study that assigns participants to a tested intervention. The registered 196 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (270% higher).
The record links to 0 conditions, and to 2 interventions - of which Bupi HCI and lipo bupi is the first listed.
NCT03731221 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03731221 about?
NCT03731221 is a clinical study titled "Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine". Patients will be randomized the day of surgery upon presentation to the operating room to either a treatment group (PECSII/SAP blocks with bupivacaine HCl plus liposomal bupivacaine) or a control group (PECSII/SAP blocks with bupivacaine HCl plus preservative free normal saline) using secure web-bas...
What is the current status of trial NCT03731221?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 196 participants. The study started on 2018-11-01. Estimated completion is 2024-09-19.
What interventions are being tested in trial NCT03731221?
The interventions under investigation include: Bupi HCI and lipo bupi (DRUG), Bupi HCI (DRUG).
Who is sponsoring clinical trial NCT03731221?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03731221's enrollment target sits among peer trials
196 70th of 2000 higher than 1,931 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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