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NCT03657368 · ClinicalTrials.gov registry record · NA
Ventilation Strategy During General Anesthesia for Orthopedic Surgery: A Quality Improvement Project
A NA study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- NA
- Development phase
- 2,860
- Enrollment target
NCT03657368: Completed NA study, sponsored by The Cleveland Clinic.
NCT03657368 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 2,860 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (104% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03657368, a NA study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,860 participants
- Enrollment target
Study Summary
The objective is to determine the optimal intraoperative ventilation strategy among the chosen tidal volume and positive end-expiratory pressure (PEEP) levels, and standardize it in an enhanced recovery pathway for orthopedic surgical patients. In particular, we propose to determine which combination of intraoperative tidal volume and positive end-expiratory pressure is best for patients having elective orthopedic surgery.
Primary Outcome
Primary outcome was oxygenation in the postoperative care unit, defined by the peripheral oxygen saturation divided by the fraction of inspired oxygen (SpO2/FiO2 ratio), a validated measure of acute lung injury.
Interventions
- PROCEDURE Low tidal Volume
- PROCEDURE High tidal Volume
- PROCEDURE Low PEEP
- PROCEDURE High PEEP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,860 participants |
| Start Date | 2018-09-03 |
| Est. Completion | 2020-10-23 |
| Phase | NA |
What the finished NCT03657368 record still lists
NCT03657368 is an interventional study that assigns participants to a tested intervention. Its 2,860 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (104% higher).
The record links to 0 conditions, and to 4 interventions - of which Low tidal Volume is the first listed.
NCT03657368 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03657368 about?
NCT03657368 is a clinical study titled "Ventilation Strategy During General Anesthesia for Orthopedic Surgery: A Quality Improvement Project". The objective is to determine the optimal intraoperative ventilation strategy among the chosen tidal volume and positive end-expiratory pressure (PEEP) levels, and standardize it in an enhanced recovery pathway for orthopedic surgical patients. In particular, we propose to determine which combinatio...
What is the current status of trial NCT03657368?
This trial is currently completed. It is a NA study. The enrollment target is 2,860 participants. The study started on 2018-09-03. Estimated completion is 2020-10-23.
What interventions are being tested in trial NCT03657368?
The interventions under investigation include: Low tidal Volume (PROCEDURE), High tidal Volume (PROCEDURE), Low PEEP (PROCEDURE), High PEEP (PROCEDURE).
Who is sponsoring clinical trial NCT03657368?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03657368's enrollment target sits among peer trials
2,860 43rd of 2000 higher than 1,958 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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