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NCT03678311 · ClinicalTrials.gov registry record · NA
Long QT Syndrome and Sleep Apnea
A NA study of Sleep Apnea and Long QT Syndrome, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT03678311: Completed NA study of Sleep Apnea and Long QT Syndrome, sponsored by The Cleveland Clinic.
NCT03678311 is a NA study of Sleep Apnea and Long QT Syndrome that has completed, run by The Cleveland Clinic. The registered enrollment target is 9 participants, below the 2,989-participant average among 36 other Sleep Apnea trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03678311, a NA study of Sleep Apnea and Long QT Syndrome, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
Obstructive sleep apnea (OSA) has been associated with cardiac repolarization abnormalities and implicated in sudden cardiac death. A biologically plausible mechanism by which OSA exerts this lethality is by QT interval prolongation, a known marker of ventricular tachyarrhythmias (VTA) leading to cardiac death. Congenital long QT syndrome (LQTS) is a familial arrhythmogenic disorder characterized by prolonged QT interval on the electrocardiogram and increased propensity for VTA. Preliminary data identify an association of the extent of severity of OSA and progressive prolongation of the corrected QT interval in LQTS.
Primary Outcome
To examine the extent that OSA severity from overnight polysomnograph is associated with corrected QT interval (QTc) from daytime 12-lead ECG. The 24 hour continuous ECG is not available.
Conditions Studied
Interventions
- DEVICE Continuous Positive Airway Pressure (CPAP)
Study Locations (1)
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2019-03-13 |
| Est. Completion | 2019-04-30 |
| Phase | NA |
What the finished NCT03678311 record still lists
NCT03678311 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 2,989-participant average among 36 other Sleep Apnea trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Sleep Apnea appearing as the primary indexed condition, and to 1 intervention - of which Continuous Positive Airway Pressure (CPAP) is the first listed.
NCT03678311 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT03678311 about?
NCT03678311 is a clinical study titled "Long QT Syndrome and Sleep Apnea". Obstructive sleep apnea (OSA) has been associated with cardiac repolarization abnormalities and implicated in sudden cardiac death. A biologically plausible mechanism by which OSA exerts this lethality is by QT interval prolongation, a known marker of ventricular tachyarrhythmias (VTA) leading to ca...
What is the current status of trial NCT03678311?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2019-03-13. Estimated completion is 2019-04-30.
What conditions does trial NCT03678311 study?
This clinical trial studies the following conditions: Sleep Apnea, Long QT Syndrome.
What interventions are being tested in trial NCT03678311?
The interventions under investigation include: Continuous Positive Airway Pressure (CPAP) (DEVICE).
Who is sponsoring clinical trial NCT03678311?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03678311 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep Apnea
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03678311's enrollment target sits among peer trials
9 36th of 36 higher than 1 of 36 other Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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