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NCT05381740 · ClinicalTrials.gov registry record · Early Phase 1
A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke
A Early Phase 1 study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 17
- Enrollment target
NCT05381740: Completed Early Phase 1 study, sponsored by The Cleveland Clinic.
NCT05381740 is a Early Phase 1 study that has completed, run by The Cleveland Clinic. The registered enrollment target is 17 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05381740, a Early Phase 1 study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 17 participants
- Enrollment target
Study Summary
The long-term goal of this project is to develop and test upper Iimb rehabilitation interventions that can improve bimanual motor function, or the ability to use both arms and hands together, for stroke survivors with moderate to severe impairment. This study will utilize a novel method of non-invasive brain stimulation in conjunction with upper limb training given for 12 visits over a period of 6 weeks. The study will include the following site visits: * Eligibility Screening and Informed Consent Visit * Baseline testing (4 visits total): 1 visit each for MRI, upper limb and bimanual motor function test, bimanual motor control, and neurophysiology related to control of the upper limbs * Repeat baseline testing (4 visits total) of MRI, upper limb and bimanual motor function test, bimanual motor control, and neurophysiology related to control of the upper limbs * 12 intervention visits during which patients will receive upper limb therapy in conjunction with non-invasive brain stimulation * Repeat testing (4 visits total) of MRI, upper limb and bimanual motor function test, bimanual motor control, and neurophysiology related to control of the upper limbs * A follow-up visit 1 month after the completion of interventions
Primary Outcome
Measure of the functional ability to perform 11 bimanual tasks scoring the spontaneous role of the affected hand, timing, and quality of movement.
Interventions
- DEVICE Novel rTMS Approach
- DEVICE Sham rTMS Approach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2022-03-08 |
| Est. Completion | 2024-01-01 |
| Phase | Early Phase 1 |
What the finished NCT05381740 record still lists
NCT05381740 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which Novel rTMS Approach is the first listed.
NCT05381740 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05381740 about?
NCT05381740 is a clinical study titled "A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke". The long-term goal of this project is to develop and test upper Iimb rehabilitation interventions that can improve bimanual motor function, or the ability to use both arms and hands together, for stroke survivors with moderate to severe impairment. This study will utilize a novel method of non-inva...
What is the current status of trial NCT05381740?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 17 participants. The study started on 2022-03-08. Estimated completion is 2024-01-01.
What interventions are being tested in trial NCT05381740?
The interventions under investigation include: Novel rTMS Approach (DEVICE), Sham rTMS Approach (DEVICE).
Who is sponsoring clinical trial NCT05381740?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05381740's enrollment target sits among peer trials
17 1351st of 2000 higher than 632 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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